According to these investigators ubiquitin activation could be inhibited or blocked at three points: (a) binding of ATP to the E1 enzyme, (b) formation of the E1-ubiquitin complex (by targeting the thiol group, (c) Interfering with the interaction between E1 and E2 enzymes (see Fig. 1)....
A novel connection between nucleotide and carbohydrate metabolism in mitochondria: sugar regulation of the Arabidopsis nucleoside diphosphate kinase 3a gene. Plant. Cell. Rep., 27: 529-534.Hammargren, J; Rosenquist, S; Jansson, C; Knorpp, C. A novel connection between nucleotide and carbohydrate ...
Describe the structure of the mitochondria and explain how this structure allows for this increase in efficiency, including details on the relationship between the important steps of cellular respirat Does catabolism include cellular respiration in its definiti...
Is there a relationship between the supramolecular organization of the mitochondrial ATP synthase and the formation of cristae? Blue native polyacrylamide gel electrophoresis (BN-PAGE) analyses of detergent mitochondrial extracts have provided evidence that the yeast ATP synthase co... MF Giraud,P Pauma...
There is hereby a well-controlled electrical separation between the wire pairs, and also a mechanical strain relief, i.e. by a primary clamping of the wire pairs themselves. By using a wedge part for insertion into the end of the cable, it can be ensured that the wire pairs extend from...
In MAMs, the distance between ER and mitochondria should be maintained between 10 nm and 30 nm, in order to allow efficient protein interactions and focused Ca2+exchange82. Some proteins are involved in the tethering—by increasing contact site formation— or spacing—by increasing the distanc...
At the molecular level, proteins residing in different organelles can interact and facilitate the formation of multi-organellar domains with new properties and functions. The distance between the ER and mitochondria was originally estimated to be approximately 100 nm [3], but later, high speed ...
VDAC is a central player in the control of the cross-talk between cytosol and mitochondria, and not only regulates the metabolic and energetic functions needed for cell survival and cell proliferation but is also involved in the control of cell death. VDAC is implicated in the induction of apop...
The intricate linking between the health of blood vessels and the functioning of neurons has attracted growing attention in the context of disorders that affect the neurological environment. Endothelial cells, forming the blood–brain barrier and blood-retinal barrier, play a fundamental role in maintai...
In principle, however, transfer of the AP-ATPase from mitochondria cannot be ruled out, assuming that the α-proteobacterial progenitor of the mitochondria, unlike Rhizobia, had an AP-ATPase with the C-terminal motif and that some eukaryotic lineages have lost this gene. The NACHT (after NAIP...