Atherosclerosis has been implicated as a cause of valvular calcification. The aim of this study was to determine whether atherosclerotic calcification in multiple vascular areas is significantly associated with aortic or mitral annular calcification independent of traditional risk factors. A total of 1242 ...
Paracrine Osteogenic Signals via Bone Morphogenetic Protein-2 Accelerate the Atherosclerotic Intimal Calcification In Vivo Objective—Vascular calcification is an important risk factor for cardiovascular diseases. Here, we investigated a role of dedifferentiated vascular smooth... Y Nakagawa,K Ikeda,Y Akaka...
This article reviews the progress of the mechanisms of sclerostin in vascular calcification and atherosclerotic heart disease, focusing on the relationship between sclerostin and vascular calcification, the impact of its concentration changes on atherosclerotic heart disease, and the effect of sclerostin ...
VASCULAR smooth muscleMUSCLE cellsEMPAGLIFLOZINARTERIAL calcificationCALCIFICATIONSGLT-2 inhibitors, such as empagliflozin, have been shown to reduce the occurrence of cardiovascular events and delay the progression of atherosclerosis. However, its role in atherosclerotic calcification remains u...
a tightly regulated process recapitulating embryonic bone formation, in this study, RNA-seq data generated from rabbit models with inherited or induced hyperlipidemia and atherosclerosis were used, to investigate bone formation related signals and biology processes in atherosclerotic vascular calcification. ...
A general term for the progressive narrowing and hardening of coronary arteries due to atheroma deposition which, with time, undergo calcification and ulceration. Risk of progression Increased cholesterol, hypertension, smoking, diabetes, family history of atherosclerotic heart disease. ...
18F-sodium fluoride positron emission tomography activity predicts the development of new coronary artery calcifications. Arterioscler Thromb Vasc Biol. 2021;41(1):534-541. doi:10.1161/ATVBAHA.120.315364PubMedGoogle ScholarCrossref 21. Doris MK, Meah MN, Moss AJ, et al. Coronary...
Calcification of Coronary Intima and Media: Immunohistochemistry, Backscatter Imaging, and X-Ray Analysis in Renal and Nonrenal Patients Coronary calcification is a potent predictor of cardiac events. In patients with chronic renal disease, both prevalence and intensity of coronary calcifica... ML Gros...
After the onset of coronary calcification, CAC scores slowly rise, commonly taking 10 to 15 years before CAC scores reach ∼100; over the next 10 to 15 years, CAC scores may grow to >1,00092,93 (Figure 2B). Analyses show the greatest prognostic value of CAC is at its low range (...
Coronary and aortic calcifications in patients new to dialysis associated with a history of coronary artery disease and atherosclerotic vascular disease (ASVD) whereas aortic calcification was significantly associated with A... DM Spiegel,P Raggi,R Mehta,... - 《Hemodialysis International International...