Vascular calcification is a highly prevalent pathophenotype that is associated with aging, atherosclerotic cardiovascular disease, diabetes mellitus, and chronic kidney disease. When present, it portends a worse clinical outcome and predicts major adverse cardiovascular events. Heavily calcified coronary and...
Vascular calcification is a highly prevalent pathophenotype that is associated with aging, atherosclerotic cardiovascular disease, diabetes mellitus, and chronic kidney disease. When present, it portends a worse clinical outcome and predicts major adverse cardiovascular events. Heavily calcified coronary and...
there are few studies that delve into the mechanisms of action, the up-regulation of Klotho in these cells could be beneficial in antagonizing the progression of atherosclerotic lesions through anti-inflammatory effects. In this sense, the expression of Klotho in these cells has been related with ...
0.824), and the sensitivity and specificity were 0.619 and 0.849, respectively. AUC, area under the curve; CI, confidence interval; LEAD, lower extremity atherosclerotic disease; ROC, receiver operating characteristic; T2D, type
Demographic data (including age, gender, weight and length) and cardiovascular risk factors (including diabetes mellitus (DM), atherosclerotic heart disease (ASHD), hypercholesterolaemia, hypertension and smoking) of all patients included were documented. Previous vascular and general surgical procedures ...
The number of patients with chronic kidney disease (CKD) has been increasing over the last decade [1]. Chronic renal failure and hemodialysis are associated with hypertension and lipid disorders that predispose to accelerated atherosclerosis [2,3]. Furthermore, atherosclerotic lesions in the aorto-il...
Cardiovascular calcification may be linked to the atherosclerotic process and resulting disease, but the sex difference regarding coronary artery disease susceptibility and calcification is incompletely understood. We thought to measure calcium volume in different chest vascular beds in very elderly men and ...
Rhein Main Vascular Center, Department of Vascular and Endovascular Surgery, Asklepios Clinics Langen, Paulinen Wiesbaden, 63225 Langen, Germany * Author to whom correspondence should be addressed. † These authors contributed equally to this work. ...
found in atherosclerotic plaques and degenerative altered aortic valves and can directly participate in the pathogenesis of these diseases, contributing to endothelial dysfunction, lipid deposition, inflammation, and osteogenic differentiation in valve interstitial cells, leading to aortic valve calcification [...
2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in Collaboration with the European Society for Vascular Surgery (ESVS): Document Covering Atherosclerotic Disease of Extracranial Carotid and Vertebral, Mesenteric, Renal, Upper and Lower Extremity ArteriesEndorsed by: The...