Negative impact on atherosclerotic vascular disease, hypertension, and heart failure Reprinted with permission from Lakatta and Levy (2003a) VSMC vascular smooth muscle cells Several studies have shown that the amount of calcification within the vascular system correlates with advanced age. Different enti...
Diabetes is associated with a marked increase of coronary heart disease. Moreover diabetic patients have more extensive and diffuse disease than non diabetic patients. This excess risk is only partially explained by the increased levels of traditional risk factors. Aim of this study was to examine ...
American Heart Association CAD: coronary artery disease CMR: cardiac magnetic resonance imaging CVD: cardiovascular disease LEAD: lower extremity arterial disease LGE: late gadolinium enhancement LVM: left ventricular mass LVSV: left ventricular stroke volume LVEF: left ventricular ejection frac...
This prospective study was conducted to correlate the presence of angiographically significant coronary artery disease (CAD) and atherosclerotic disease in the aorta, carotid, and femoral arteries as measured by ultrasound. One hundred two consecutive patients admitted for coronary angiography for suspected...
Heart-healthy diets and LDL aggregation susceptibility Increased aggregation susceptibility of LDL particles has been found to increase the risk of ASCVD events independently in patients with CAD and peripheral artery disease [14, 47]. In order to clarify the potential mechanisms behind aggregation susce...
However, the expression and function of sEVs-derived circRNAs in coronary heart atherosclerotic disease (CAD) remain unknown. In this study, we investigated global changes in the expression patterns of circRNAs in sEVs from CAD-related monocytes and identified circNPHP4 as a significantly up...
6-8 Discerning the physiologic significance of a stenosis is a major goal of stress testing and is fundamental to guide management of ischemic heart disease. Anatomic approaches focusing on the detection of a stenosis are often considered incomplete without incorporation of physiologic parameters. To ...
Cardiovascular disease (CVD) remains the leading cause of death globally and an ageing world population is expected to increase the burden of CVD further. Among older adults, CVD is also a major cause of disability, functional decline, loss of independen
Erqou S, Kaptoge S, Perry PL, et al; Emerging Risk Factors Collaboration. Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality. JAMA. 2009;302(4):412-423. doi:10.1001/jama.2009.1063PubMedGoogle ScholarCrossref ...
In acute chest pain patients, coronary CTA is becoming an effective primary modality for the exclusion of obstructive CAD.16 Non-contrast CCS CT is recommended in both low-risk patients with a family history for ischemic heart disease and in intermediate-risk patients. For an extensive over...