Furthermore, we found that ataxin-2-like is a component of stress granules. Interestingly, sole ataxin-2-like overexpression led to the induction of stress granules, while a reduction of stress granules was detected in case of a low ataxin-2-like level. Finally, we observed that ...
Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding ...
As discussed above, each of the invention A2BP proteins bind to ataxin-2, ataxin-2 like proteins or to nucleic acid. The A2BP set forth in SEQ ID NO:2 was identified in a screen of binding proteins using ataxin-2, and are contemplated as being involved in the signal transduction ...
Last year, two independent and largely similar studies demonstrated that reduced Ataxin-2 levels in mice predisposed them to ALS-like illness, and slowed down their onset and progression of neurodegeneration. Taking cues from these studies, Baskar and colleagues wondered if reduced neurodegeneration cou...
kl966Hu02 唾液酸结合Ig样凝集素1(SIGLEC1)多克隆抗体 Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 1 (SIGLEC1) kl171Ga01 转铁蛋白受体(TFR)多克隆抗体 Polyclonal Antibody to Transferrin Receptor (TFR) 标题: 内容: 联系人: 联系电话: ...
Ataxin-2 has two other characteristic domains, including the N-terminal LSm (Like Sm) domain, which binds directly to specific sequences in mRNAs, and the C-terminal PAM2 motif, which binds to the major cytoplasmic poly(A) binding protein PABPC1 [1,2]. Ataxin-2 upregulates protein ...
Increasing levels of wild-type ataxin-1 are sufficient to alter certain features of agility37 and have been shown in some models to lead to SCA1-like neurodegeneration34,35,36, and thus the exact balance of binding partner selection by ataxin-1 appears to be of critical importance. With ...
Mouse Putative ataxin-7-like protein 3B (ATXN7L3B) ELISA Kit检测范围:0.156 ng/ml - 10 ng/ml 保存建议 4℃下运输。收到该Mouse Putative ataxin-7-like protein 3B (ATXN7L3B) ELISA Kit产品后,按照试剂盒手册中的储存说明储存试剂盒。
英文名称:Ataxin 7 Like 1 (ATXN7L1) Antibody (FITC),中文名称:Ataxin 7样1(ATXN7L1)抗体(FITC),产品货号:Catalogue No: abx312253,ATXN7L1抗体(FITC)是一种兔抗ATXN7L1的多克隆抗体,与FITC结合。目标ATXN7L1反应性人宿主兔克隆性多