Ataxiais defined as an inability to generate a normal or expected voluntary movement trajectory that cannot be attributed to weakness or involuntary muscle activity (chorea, dystonia, myoclonus, tremor) about the affected joints. Ataxia can result from impairment of spatial pattern of muscle activity ...
Cerebellar ataxia is defined as lack of accuracy or coordination of movement that is not due to paresis, alteration in tone, sensory loss, or the presence of involuntary movements. From:Textbook of Clinical Neurology (Third Edition),2007
Transcranial magnetic stimulationCerebellar ataxia(CA) is defined as a degenerative disease of the nervous system. Repetitive transcranial magnetic stimulation (rTMS) has been a promising treatment for neurological and psychiatric diseases. Hence, to find out whether cerebellar rTMS impacts CA as a ...
Acute ataxia in childhood is often caused by toxin ingestion. With the increasing number of paediatric patients on antiretroviral medication, we observe more side-effects of these drugs. Acute ataxia is defined as unsteadiness of walking or fine motor movement of <72 hours. The most common causes...
FRDA is usually defined as a neurological disorder, but most patients die from cardiomyopathy. The gene responsible for FRDA was identified by positional cloning and encodes a relatively small protein of 210 amino acids (4). The gene itself is small, encompassing only five exons. The most ...
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4b receives noise and a class vector as conditions and embeds them into vectors before delivering them to G. In Fig. 4c, D is composed of an image discriminator (DI) and a video discriminator (DV). DI determines whether an individual trajectory is real or fake, while DV assesses the ...
First described over 80 years ago, ataxia-telangiectasia (A-T) was defined as a clinical entity 50 years ago. Although not encountered by most clinicians, it is a paradigm for cancer predisposition and neurodegenerative disorders and has... Martin,F,Lavin - 《Nature Reviews Molecular Cell Biolog...
This scoping review aims at analysing data pertaining to strategies that were implemented for rare neurological diseases and neurometabolic disorders care during COVID-19 pandemic, as well as the impact of these strategies. The present work is part of the results of the European Brain Council (EBC...
Although the pathogenesis of A-T is still not understood, it has been suggested that accumulated oxidative stress plays a critical role as in otherneurodegenerative diseases[62]. ATM (−/−) astrocytes andneural stem cellsexhibit growth defects and higher levels of senescence as well as ...