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This study introduces the term ferroptosis to describe a novel form of non-apoptotic cell death and identifies the small molecule ferrostatin 1 as the first specific inhibitor of ferroptosis. Article CAS Google Scholar Ganz, T. Systemic iron homeostasis. Physiol. Rev. 93, 1721–1741 (2013). ...
Define the following term: "opisthorchis felineus". Identify the term/concept described by the following statement. Hemoglobin binding of oxygen is best described as a combination of sequential and ___ model. A. Bohr B. 2, 3-BPG C. Carbamate D. Carbon dioxide E. ...
1(a). The first group is composed of high-frequency repeats, also known as satellite DNA sequences (satDNAs), which are found in various regions of the chromosomes, including pericentromeric, subtelomeric, and interstitial regions. These sequences typically form constitutive blocks of ...
All deciduous teeth are usually visible at birth in the term neonate, although the incisors may not have completely erupted through the oral mucosa. Most adult New World camelids have 30 or 32 permanent teeth. Their dental pattern per side is as follows: Empty CellIncisorsCaninesPremolarsMolars...
Friedreich’s ataxia is a rare, progressive genetic neurodegenerative disease and involves a defect in thenuclear factor (erythroid-derived 2)-like 2 (Nrf2)antioxidant signaling pathway (Abeti et al.2018). Suppression of theNrf2signaling pathway leads to oxidative stress, mitochondrial dysfunction, and...
Cajal first used the term in 1913: he observed disintegration of the distal cell processes of astrocytes, along with a fragmentation or beading of proximal processes closer to the astrocyte cell body. In contemporary clinical and experimental reports, clasmatodendrosis has been observed in models ...
, dizziness, loss of consciousness, ataxia, and epilepsy. SARS-CoV-2 is capable of infecting human cells through the binding of its surface protein Spike1 to host cell surface proteins. The angiotensin converting enzyme-2 (ACE2) functions as a receptor for the virus and its main gateway. ...
Although the term “ferroptosis” was first coined by Dixon et al. in 2012 (Fig.1a), a similar form of neuronal cell death triggered by cysteine depletion called “oxytosis” was reported by Murphy et al. back in 1989;8this neuronal cell death was induced by the excitotoxin glutamate by...
Mitochondria are the centers of energy and material metabolism, and they also serve as the storage and dispatch hubs of metal ions. Damage to mitochondrial structure and function can cause abnormal levels and distribution of metal ions, leading to cell d