Longevity estimates for a subset of purebreds are visualised in Fig.3. Significant variation in longevity was evident between breeds (p < 0.001): those most at risk from early death included Caucasian Shepherd Dog (x̃ = 5.4, HR 2.4, 1.6–3.7), Presa Canario (x̃ = 7.7,...
The Dog-Human Relationship In addition to tameness, another unique trait of dogs is their ability to understand humans. For example, if you point or even shift your gaze toward a certain object (say, a jar that contains dog treats), a dog will likely investigate the object (Hare & Tomasel...
RPE65 gene therapy slows cone loss in Rpe65-deficient dogs Gene Ther, 20 (2013), pp. 545-555 CrossrefView in ScopusGoogle Scholar 21 K. Narfstrom, M.L. Katz, R. Bragadottir, et al. Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog ...
like human narcolepsy [64]. The bottom dog on therightis having a complete attack of cataplexy, an episode of complete muscle paralysis while awake that has been triggered
However, QTL mapping is a step prior to gene definition and QTL region information is roughly defined based on phenotype information. As the variance of QTL length was very large and longer QTL tended to have higher deletion scores (Additional file 17), we could not determine whether high ...
Figure 2. Cladogram for the Inferred Haplotypes in the Resequenced Region of STAT2 The nomenclature of the haplotypes follows Table 1. Nonsynonymous mutations are indicated with a cross hatch if they are predicted as benign and with a cross within a circle and the name of the gene if they ...
However, QTL mapping is a step prior to gene definition and QTL region information is roughly defined based on phenotype information. As the variance of QTL length was very large and longer QTL tended to have higher deletion scores (Additional file 17), we could not determine whether high ...
Although the animals have a normal phenotype, they are affected by impaired fertility, oestrous cycle disturbances, and an extended inter-birth interval. In carriers of centric fusions, meiosis is disrupted. In our study, the most common form of karyotype found in blue foxes had 49 diploid ...
mutants (Samba) for this gene [43]. This implies that the observed deafness phenotype is in part due to the protein affecting OHC function [43], a cell type unique to mammals. It is likely that the several PSSs found in this study contributed to shape this protein function in mammals. ...
we suggest that evolution of resistance to PCBs in fish may converge on a common target gene, AHR2, but that the specific molecular changes may differ between species, and perhaps also within a species among populations that have independently evolved the resistant phenotype (for other examples, ...