ASTCT CR分级标准(ASTCT Criteria for CRS Grading)如下: 1. CR0(无症状) -体温≤38℃ -心率≤90次/分钟 -血压正常 -没有症状、体征或实验室异常 2. CR1(轻度症状) -体温>38℃,但≤39℃ -心率>90次/分钟 -血压正常或轻度升高 -有轻度的让人不适感,但没有需要治疗的症状 -实验室检查出现轻度的白细...
Results According to the ASTCT grading, B-ALL pts had 87% CRS (28% grade ≥3), while DLBCL pts had 86% CRS (14% grade ≥3) with axi-cel, and 54% (no grade ≥3) with tisa-cel. B-ALL pts had 55% ICANS (45% grade ≥3), while DLBCL pts had 55% ICANS (33% grade ≥3)...
SYMPTOMS DEFINING CRS MUST BE ATTRIBUTED TO IMMUNE EFFECTOR CELL ENGAGEMENT TOXICITIES EXCLUDED FROM THE DEFINITION OF CRS LABORATORY PARAMETERS ARE NOT INCLUDED IN THE DEFINITION OR GRADING OF CRS IMPLICATIONS OF A GRADING SYSTEM BASED ON PRACTITIONER INTERVENTION CONSENSUS ON CRS GRADING CRS SEVERITY ...
Yet despite this dissemination of and evaluation on individual REMS training decks with variable product- and manufacturer-specific grading schema and management algorithms, each treatment center has typically adopted one internally vetted management algorithm per toxicity syndrome, such as CRS, immune effec...