The N2 Bristol strain served as wild-type. If not stated otherwise, all experiments were performed at day 1 of adulthood, and the examined worms were all hermaphrodites. Integration of the extrachromosomal arrays of the cpl-1WT::yfp and cpl-1*::yfp strains obtained from Gary Silverman13 was...
Here we find that proline, a highly abundant amino acid in collagen proteins, is newly synthesized from glutamine in CAFs to make tumour collagen in breast cancer xenografts. PYCR1 is a key enzyme for proline synthesis and highly expressed in the stroma of breast cancer patients and in CAFs...
ns not significant. n = 3/group. Source data are provided as a Source Data file. Full size image The use of Capillary Isoelectric Focusing (cIEF) allowed us to determine the isoelectric point (pI) of AAV8 and AAVv128. The measured pI of AAVv128 was 7.6930, which was significantly ...
Theodor That's definitely not the behavior I'm getting. I created and annotated a video with what I get for you here, so you can see how it works for me.https://www.youtube.com/watch?v=cuSXPkCJlKo The video starts with me having an invalid token (it's ...
randomized double-blinded trials enrolling 5866 patients and 14 drugs reported a certain advantage for individual substances in specific cognitive domains without finding overall superiority [51]. It should be mentioned here that some recently approved antipsychotics were not included in this meta-analysis...
Similarly, a small Norwegian study of GPA patients receiving rituximab maintenance therapy did not find any association between CNSAC and relapse risk [79], likely due to methodological differences: concomitant antibiotics were allowed in this study and the overall frequency of SA carriers was ...
Here we present the first atomic structures of a gammaherpesvirus portal vertex in KSHV, which allowed us to use structure-guided mutageneses to identify a viable drug target. Simultaneously, our method of symmetry relaxation and sequential localized classification enabled us to dissect a heretofore ...
Process measurement includes but is not limited to compliance with insertion bundles, CVC utilization by insertion site or type (eg, femoral catheters vs other CVC sites; PICCs vs centrally inserted lines), the con- dition of CVC dressing and tim...
I am using query "{searchboxquery} Sites contentclass: STS_Site " in PnP search result webpart's query parameter. Here, Sites is name of Sites webpart. (I should fetch associated sites from sites webpart or not I am not sure) Can anyone please help me to ge...
Mycobacteriophages are a diverse group of viruses infecting Mycobacterium with substantial therapeutic potential. However, as this potential becomes realized, the molecular details of phage infection and mechanisms of resistance remain ill-defined. Here