ASMTL-AS1HuRrenal cell carcinomaursolic acidVEGFIt has been reported ursolic acid (UA), one of the naturally abundant pentacyclic triterpenes, possesses a wide range of biological activities including anti-inflammatory, anti-atherosclerotic, and anticancer properties. Renal cell carcinoma (RCC) ...
Functional studies suggested that ASMTL-AS1 inhibits proliferation, migration, and invasion of HGC-27 and NCI-N87 cells by regulation of miR-1270. In summary, ASMTL-AS1 and miR-1270 are associated with poor prognosis of patients with gastric cancer. ASMTL-AS1 inhibited gastric cancer ...
Mechanistically, ASMTL-AS1 could act as a competing endogenous RNA for microRNA-342-3p (miR-342-3p) and inhibit its activity in OS cells, consequently causing an increase in ADAM metallopeptidase domain 9 (ADAM9) levels. Furthermore, inhibiting miR-342-3p or upregulating ADAM9 abated silenced...
long non-coding RNARNA sequencingbioinformatics analysisbiomarker>DIAGNOSISDEMENTIAPROTEINGENEABSTRACTdoi:10.1080/01616412.2023.2203616View further author informationmaml166@163.comLong MaView further author informationChang YangView further author information...
Also, ROC analysis showed that SNHG7 was a relatively good promising biomarker (AUC=0.73, p value=0.02), while ASMTL-AS1 (AUC=0.92, p value<0.0001) and LINC02604 (AUC=1.00, p value<0.0001) emerged as excellent diagnostic biomarkers in colorectal cancer.It seems that increased expression ...