Importantly, the regulatory axis of ASMTL-AS1/miR-93-3p/miR-660/FOXO1 was also identified in vivo. Collectively, our data clearly indicate that ASMTL-AS1 functions as a novel tumor suppressor in PTC through regulation of miR-93-3p/miR-660/FOXO1 pathway. Targeting ASMTL-AS1 and its ...
ASMTL-AS1HuRrenal cell carcinomaursolic acidVEGFIt has been reported ursolic acid (UA), one of the naturally abundant pentacyclic triterpenes, possesses a wide range of biological activities including anti-inflammatory, anti-atherosclerotic, and anticancer properties. Renal cell carcinoma (RCC) is a ...
Functional studies suggested that ASMTL-AS1 inhibits proliferation, migration, and invasion of HGC-27 and NCI-N87 cells by regulation of miR-1270. In summary, ASMTL-AS1 and miR-1270 are associated with poor prognosis of patients with gastric cancer. ASMTL-AS1 inhibited gastric cancer ...
long non-coding RNARNA sequencingbioinformatics analysisbiomarker>DIAGNOSISDEMENTIAPROTEINGENEABSTRACTdoi:10.1080/01616412.2023.2203616View further author informationmaml166@163.comLong MaView further author informationChang YangView further author information...
Also, ROC analysis showed that SNHG7 was a relatively good promising biomarker (AUC=0.73, p value=0.02), while ASMTL-AS1 (AUC=0.92, p value<0.0001) and LINC02604 (AUC=1.00, p value<0.0001) emerged as excellent diagnostic biomarkers in colorectal cancer.It seems that increased expression ...