Asian-American men who possess ALDH2*2 alleles and who experience a facial flush after consuming alcohol were carefully matched on drinking history and demographic variables with nonflushing Asian males with only ALDH2*1 alleles. Each man was tested following placebo and a challenge dose of 0.75 ...
Esophageal squamous cell carcinoma (SCC) in East Asians is characterized by field cancerization in the upper aerodigestive tract (UAT: esophagus and head and neck region) and stomach. In addition to alcohol consumption, smoking, and a low intake of fruit and vegetables, the combination of slow-m...
The high prevalence ofALDH2*2allele in East Asian populations may have important public health implications and may be utilized to reduce the occurrence of alcohol-related cancers among East Asians, including: 1) Identification of individuals at high risk of developing alcohol-related cancers by ...
People vary widely in how they respond to medications, and this is true of medications for alcoholism, Ray said. Naltrexone can reduce the stimulating feelings of alcohol; patients onnaltrexoneoften report that their alcohol 'high' is not as pleasant, which helps them reduce their drinking, she...
The editorial by Freedman et al states "epidemiologic literature suggests that those who begin drinking at an early age may be at greater risk for a maladaptive and more genetically pronounced form ofalcohol consumption, and other environmental milieus affect the risk of alcoholism." It will be ...
Hepatitis B virus, tobacco smoking and ethanol consumption in the etiology of hepatocellular carcinoma Tobacco smoking and alcohol drinking histories were obtained from 194 patients with hepatocellular carcinoma (HCC) and 456 hospital controls, and the resul... D Trichopoulos,A Tzonou,E Kaklamani,....
Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions. Alcohol drinking is a major risk factor for esophageal cancer in Japan and its impact may ...
an ALDH2 deficiency (缺乏). It prevents their bodies from treating alcohol the way other people do. But the effects might be more serious than just a red face. Researchers warn of a link between this condition and an increased risk of cancer of the esophagus (食道) from drinking alcohol....
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Social status, gender and alcohol-related problems: the black young adult experience While blacks are not as engaged in risky/heavy drinking, they are not shielded from problems conditional on drinking patterns. Focus on alcohol-related ... DC Godette,E Edwards,CL Ford,... - 《Ethnicity & He...