Fig. 1. Grand averages of ERPs elicited by a modified auditory oddball paradigm in 15 subjects with ALDH2'1/2'1 and 14 subjects with ALDH2'1/2'2 genotypes following oral administrationof placebo. Averages are presented for frontal (Fz), central (Cz), and parietal(Pz) leads over the ...
These data suggest flushers, those with at least one ALDH2*2 allele, have less of slow-alpha wave EEG response to alcohol than nonflushers with ALDH2*1/2*1 genotype. 展开 关键词: EEG ALCOHOL ALDEHYDE DEHYDROGENASE (ALDH ASIANS GENETICS FLUSHING ...
Environmental factors, which are acquired and modifiable, associated with AD include smoking status, alcohol consumption, diet, and physical activity [3]. On the other hand, the heritability of AD is approximately 70%, and genetic factors are inborn and nonmodifiable [4, 5]. However, knowing ...
会议名称: Joint Scientific Meeting of the Research-Society-on-Alcoholism and the 会议时间: 2008/06/01 收藏 引用 批量引用 报错 分享 全部来源 求助全文 ResearchGate 相似文献Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism The alcohol-flush reaction occurs in Asians who inherit the ...
Although the relationship between the conventional ACEs and mental health issues in adulthood have been well investigated, the more recent potential constructs of ACEs should be further explored27. Few studies have examined long-term effects of a wide range of ACEs in Asians. In Japan, the ...
Alcohol, Eyes and VisionVitamin B1, B12 and folate deficiency, common in chronic alcoholics, may result in a damage of the optic nerve (optic neuropathy) with reversible vision loss [1].In individuals with diabetes type 2, chronic heavy drinking is associated with loss of visual acuity [2]....
NPI- 031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. Pharmacol Biochem Behav 2003; 75: 619–5. 34 Zheng J, Chen B, Jiang B, Zeng L, Tang ZR, Fan L, et al. The effects of puerarin on CYP2D6 and CYP1A2 activities in ...
Index, but no apparent horizontal pleiotropy or outlier was discovered using the MR Egger and MR-PRESSO approaches. In the multivariable MR analysis that mutually adjusted tobacco smoking and alcohol drinking, Table2displayed the independent effects of genetically predictedSmkInitandSmkCeson CRC risk. ...
摘要: This review aimed to inform the current state of alcohol research on the joint effects of genes and the environment conducted in U.S. racial/ethnic minority populations, focusing on African Americans, Latinos/Hispanics, Asians, and American Indians....
In this context, we aimed to assess the effects of allelic variation at the A118G SNP on a range of pharmacodynamic markers of rewarding consumption of alcohol and food, and to explore the potential pharmacogenetic interaction between OPRM1 genotype and μ-opioid receptor antagonism by both NTX ...