aeruginosa is resistant to almost all classes of β-lactams, except the carbapenems [36]. Two mechanisms contribute to the high expression level of ampC, induction and derepression. In the case of induction, when P. aeruginosa encounters specific β-lactams or β-lactamase inhibitors that can ...
aclasses of new features can be implemented in a repeatable and well defined way e.g., frameworks, device drivers that implement a standard interface, systems with a plug-in architecture. 新的特点类在反复性可以被实施,并且好的defined方式即,框架,实施一个标准接口的设备驱动程序,系统以插入式...
A reconstruction of substrate-bound Cdc48 (EMD-20136)18 was imported into cryoSPARC, low pass filtered to 40 Å, and used as the basis for heterogeneous refinement in cryoSPARC to sort particles into multiple classes. Resulting 3D classes revealed asymmetric, symmetric, and junk classes. A ...
In nature, several classes of enzymes catalyze oxidative halogenation reactions that install halogen substituents (X = Cl, Br, I) into diverse structures starting from distinct precursors5,6. The high selectivity, mild reaction conditions, and environmentally benign oxidants and halogen sources ...
While there are many general reagents (anthrone, triphenyltetrazolium chloride), it is fortunate that the various classes of sugars (pentoses, hexoses, amino sugars, deoxysugars, uronic acids) respond differently to color tests, as these are generally easy to carry out with the aid of standard ...
While [NiFe]-hydrogenases can be found in all major phyla of the prokaryota, [FeFe]-hydrogenase distribution is focused on the classes of δ-Proteobacteria, Clostridia and Thermotogae [30]. [FeFe]-hydrogenases are also identified among the eukaryota including several amitochondriate, anaerobic pro...
an auxin analog found in the seeds of some leguminous plants4. While maytansine was recently confirmed to be produced by endophytic bacteria5, the synthesis of 4-chloroindole-3-acetic acid may also rely on symbiotic bacterial metabolism, as known classes of indole halogenases, which are well ...
(Supplementary Figure5). Structural differences in their environment must therefore account for the loop-flexibility that enables the translocation of C367 in CbA5HWT. The most prominent differences between standard hydrogenases and CbA5HWTnear the TSC-loop concern the residues at positions 364 (...
Electrocatalytic mechanism of reversible hydrogen cycling by enzymes and distinctions between the major classes of hydrogenases Proc. Natl. Acad. Sci. U. S. A., 109 (2012), pp. 11516-11521 CrossrefView in ScopusGoogle Scholar [62] S.T. Stripp, G. Goldet, C. Brandmayr, O. Sanganas,...
No additional density for the Pan3 N termini can be observed in the reference free 2D classes of the full-length Pan2-Pan3 data. (B) 3D reconstruction of the Pan2cat-Pan3Δ(1-162) data with rigid body fitted models of Pan2-Pan3. The coloring scheme resembles that outlined in Figure...