【Key words】TMS1/ASC gene Tumor Apoptosis 近年研究认为癌的发生与细胞凋亡过程的抑制有关。在细胞凋亡的信号通路中ASC家族具有重要地位。本文就ASC基因与肿瘤相关性研究进展做一简单综述。 1 ASC的结构与功能 ASC基因是由MASUMOTO和CONWAY在分别研究白血病和乳腺癌时分离鉴定的一个新的与凋亡有关的抑癌基因,ASC基...
Japanese medaka (Oryzias latipes)gene expressionASC is a component of the inflammasome playing crucial roles in the inflammatory response. In mammals, ASC induces pyroptosis and inflammatory cytokine production. In this study, three asc genes (asc1, asc2, and asc3) from the Japanese medaka (...
The ASCL1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, and frog. 180 organisms have orthologs with human gene ASCL1. All MASH1/ASCL1 genes MASH1/ASCL1 cDNA/ 유전자 기능 This gene encodes a member of the basic helix-loop-helix (BHLH) ...
The yeast CPC2/ASC1 gene is regulated by the transcription factors Fhl1p and Ifh1p. Curr Genet 2006;49:218-228. [PubMed: 16402205]Kleinschmidt, M., Schulz, R., and Braus, G. H. (2006) The yeast CPC2/ASC1 gene is regulated by the transcription factors Fhl1p and Ifh1p. Curr ...
PYCARD (ASC) cloned gene : ORF from ATG to Stop, in pUNO1 expression plasmid selectable in E.coli and mammalian cells. Fully sequenced.
Herein, we have developed an optogenetic toolbox fused to the catalytic domain (CD) of DNA-methyltransferase3A (DNMT3A-CD) or Ten-Eleven Dioxygenase-1 (TET1-CD) for loci-specific alteration of the methylation state at the promoter ofAscl1 (Mash1), a candidate proneuron gene. Optogenetical ...
like protein containing a CARD (ASC), whereas Z-VAD-fmk, a pan-caspase inhibitor, blocked the cell death after the oligomerization. Silencing of the ASC gene (Pycard) by small hairpin RNA treatment inhibited the NLRP3 mutant-induced cell death, but silencing of the caspase-1 gene (Casp1)...
浓度:600 ug/ml 库存:现货 点击咨询售前客服 点击咨询售后客服 humanWB,IHC KD Validated View Article humanWB Cancer Res Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity. See more citations...
Gene ID: 51008 种属 Homo sapiens 基因序列编号: NM_001198799.3 基因描述 Homo sapiens activating signal cointegrator 1 complex subunit 1 (ASCC1), transcript variant 1, mRNA DNA编码区: atggaagttctgcgtccacagcttataagaattgatggccggaattacaggaagaatcca gtccaagaacagacctatcaacatgaagaagatgaagaggacttctatcaaggctc...
We have found the absence of TMS1/ASC expression in human breast cancer because of methylation of TMS1/ASC gene. 甲基化诱导静止基因(TMS1/ASC)是一新发现的抑癌基因,可编码pyrin区(a pyrin domain,PYD)和引起caspase聚集的caspase聚集区(a caspase recruitment domain,CARD)二种蛋白—蛋白相互作用区,而...