Doxycycline (200 μg/ml) was administered ad libitum in drinking water from Day 0 and tumour growth was measured twice weekly until individual shControl tumours reached ~ 1000 mm3, when all the mice were humanely euthanized in accordance with ethics approval protocol 2013/030 A from Sydney ...
Nam Doo Kim2, Seongkeun Jeong3,Yunjin Jung3, Jae Young Choi4, Hyun Ho Park4 & Joo Young Lee1 Gouty arthritis is caused by the deposition of uric acid crystals, which induce the activation of NOD- like receptor family, pyrin domain containing 3(NLRP3) inflammasome....
a, Schematic of timeline required to establish, propagate, edit and select for organoids harboring mutations in cancer-associated genes before transplantation into immunocompetent hosts for tumor establishment.b, Representative microscopy ofPten−/−;Trp53−/−;cMycT58A(PtPM) organoids, and s...