considering the possibility of large flow variations. A bottleneck analysis is crucial. It must also take into account moving bottlenecks such as floats, but also the operation of police or emergency vehicles. Confluence, turning and intersection points should be determined....
“The anti-obesity medications and their effect on cardiometabolic health are creating an entire new frontier where we can make progress,” Krumholz explained. “The prevention area is also exploding with new ideas, new targets, new opportunities, with ways to treat people that may be intermittent...
the study highlights the feasibility and safety of this approach by demonstrating no adverse off-target effects or side effects, making it a potentially promising treatment for T-ALL patients who have limited options. The research presents a significant advancement in CAR T-cell therapy by addressing...
Every budding nanoethicist should be made to read Daniel Callahan’s wise and humble 1973 essay “Bioethics as a Discipline” for a sense of how to approach the unknown and unknowable in a serious and organized way. Nanoethics, as it has begun to take shape, lacks exactly this sense of ...
Our work also demonstrated the potential for BC spheroids to be used as building blocks to create 2D and 3D shapes and create patterns that could find use as functionalised ELMs. The building block approach opens a myriad of applications, especially when considering the possibility of using BC sp...
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Despite the idea that necrosis is an uncontrolled or default form of cell death, accumulating studies have suggested that this may not be true. Rather, it appears that necrotic cell death can be a regulated event that contributes to development and to the maintenance of organismal homeostasis. Te...
Our findings might have additional translational relevance for a number of possible reasons. First, there is the possibility that measurement of circulation NET-derived products (i.e., CitH3) could represent an easily measurable plasma biomarker of asthma severity. In this context, we have found ...
up, when the densities become so high that they cause contact forces between bodies to add up. This ultimately implies a sudden onset of ‘crowd turbulence’. Under such conditions, the sizes and directions of forces acting on the bodies of visitors move them around in an uncontrolled way, ...