The hyaline articular cartilage is composed of chondrocytes surrounded by a large extracellular matrix (ECM). The ECM is composed of water and two groups of macromolecules: proteoglycan (PG) and collagen fibers. These macromolecules restrict the motion of water protons. Changes to the ECM precede ...
Articular cartilage is composed of articular chondrocytes and extracellular matrix and has no blood vessels, lymphatics, or n erves3,4. Thus, articular chon- drocytes are responsible for the maintenance of articular cartilage. Osteoarthritis (OA) is a major joint disease that causes joint ...
- type X collagen is present mainly in the calcified cartilage layer and inhypertrophic zoneof the growth plate; - much of hyaline cartilage in non articular areas of the body ultimately calcifies w/ maturation; - when calcification occurs,chondrocytesdie & matrix disintegrates; - articular cartil...
Articular cartilage is composed of articular chondrocytes and extracellular matrix and has no blood vessels, lymphatics, or n erves3,4. Thus, articular chon- drocytes are responsible for the maintenance of articular cartilage. Osteoarthritis (OA) is a major joint disease that causes joint ...
Articular cartilage is mainly hyaline articular cartilage. It is an avascular and aneural tissue; thus its potential for healing is limited—if not nonexistent.
The key difference between articular cartilage and meniscus is that articular cartilage is a type of cartilage found in the knee, ankle, hip, shoulder, elb
Articular cartilage is distinguished by the unique alignment of type II collagen, a feature crucial for its mechanical properties and function. This characteristic organization is established during postnatal development of the tissue, yet the underlying mechanisms remain poorly understood. In this study,...
Normal articular cartilage is made up of 80% water. Cartilage is an elastic, resilient structure that acts as ashockabsorber to protect the underlying bone. The properties of articular cartilage depend on the composition and structure of theextracellular matrix, and the synthesis and maintenance of...
The concept of femoroacetabular impingement syndrome (FAIS) has received much attention over the past 20 years. Currently, it is believed that FAIS can lead to intra-articular pathologies such as labral tears and articular cartilage lesions, resulting in clinical symptoms and subsequent poor clinical ...
Cartilage tissue engineering is complex owing to the apt choice of biopolymers, cell source and dynamic simulation. Herein, we elucidate a novel approach to mesenchymal stem cells (MSCs)- induced chondrogenesis using microfluidics on an organ-on-a-chip (OOAC) model, coupled with decellularized extr...