Articular cartilage functions to provide a low‐friction surface for joint movement for many decades of life. Superficial zone protein (SZP) is a glycoprotein secreted by chondrocytes in the superficial layer of articular cartilage that contributes to effective boundary lubrication. In both cell and ...
Cartilage is an elastic, resilient structure that acts as ashockabsorber to protect the underlying bone. The properties of articular cartilage depend on the composition and structure of theextracellular matrix, and the synthesis and maintenance of this matrix is dependent on thechondrocytes. ...
One of the functions of articular cartilage is joint lubrication. Cartilage has an extremely low co-efficient of friction, which can be further reduced by elastic deformation, synovial fluid, fluid-film formation and efflux of fluid from cartilage. Synovial fluid is essentially an ultra-filtrate of...
After injury, articular cartilage is unable to naturally restore itself back to a functional tissue, and, because of this, current efforts have been directed toward tissue engineering. Since articular cartilage contains zones that are specific in their functions, the replication of these zones may ...
The main functions of cartilage are to protect the subchondral bone from mechanical damage, to prevent abrasive wear between the bone extremities, and to provide low-friction bearing surfaces. Therefore, the mechanics of load transmission and the mechanical properties of cartilage influence its ability...
Articular cartilage functions as a wear-resistant, smooth, nearly frictionless, load-bearing surface. The composition and physiochemical properties of articular cartilage, the fundamental organization of the collagen network, and the molecular organization of collagen and...
- functions ofcollagenfibers w/ in cartilage: - provides tensile strength to tissue and resist movement of interstitial water &proteoglycansfrom the cartilage, esp. while it sustains compressional loading; - to anchor ground substance of articular cartilage to subchondral bone; ...
Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens ...
Mammalian articular cartilage serves diverse functions, including shock absorption, force transmission and enabling low-friction joint motion. These challenging requirements are met by the tissue's thickness combined with its highly specific extracellular matrix, consisting of a glycosaminoglycan-interspersed co...
surgery to replace the joint is frequently done to treat significant cartilage deterioration these days. However, the materials that are being used for replacement have high friction coefficients, lack shock absorption functions, ...