3,94,95 Proteoglycans have a unique bond with water that allows articular cartilage to resist and distribute compressive forces. The quantity of proteoglycans in articular cartilage depends on joint location, with weight-bearing joints having a higher proteoglycan content than non–weight-bearing joints...
Gurr E, Mohr W, Pallasch G: Proteoglycans from human articular cartilage: the effect of joint location on the structure. J Clin Chem Clin Biochem 1985;23:811-819.E. Gurr, W. Mohr and G. Pallasch, Proteoglycans from human articular cartilage: the effect of joint location on the str...
The function, composition, and structure of articular cartilage should be thoroughly understood before repairing articular cartilage injury. Under normal physiological conditions, articular cartilage is smooth and elastic, which cushions stress well to keep the joint sliding. The physiological properties of ...
and must be highly individualized to ensure successful outcomes. These programs are designed according to the knowledge of basic science, anatomy, and biomechanics of articular cartilage as well as the biologic course of healing after surgery. The goal is to restore full function in each patient ...
The in vivo measurement of articular cartilage deformation is essential to understand how mechanical forces distribute throughout the healthy tissue and change over time in the pathologic joint. Displacements or strain may serve as a functional imaging b
total chondrocytes in different regions of AC inh. Data were analyzed using two-way ANOVA Tukey’s post hoc test.jThe correlation of trabecular pattern factor (Tb. Pf) of the SB and the percentage of pSmad2/3+cells in the above cartilage at the same location.h–jn = 6 biologically...
Melrose J, Roughley P, Knox S, Smith S, Lord M, Whitelock J (2006) The structure, location, and function of perlecan, a prominent pericellular proteoglycan of fetal, postnatal, and mature hyaline cartilages. J Biol Chem 281:36905–36914 Article PubMed CAS Google Scholar Melrose J, Hayes...
Cartilage immunoprivilege depends on donor source and lesion location. Acta Biomater. 23, 72–81 (2015). CAS PubMed PubMed Central Google Scholar Koh, J. L., Kowalski, A. & Lautenschlager, E. The effect of angled osteochondral grafting on contact pressure: a biomechanical study. Am. J....
The main function ofarticular cartilageis to provide a smooth surface betweenbone tissuesand to facilitate the transfer of loads with a lowfriction coefficient[1]. Therefore, the integrity of its function is essential forjointhealth, andarticular cartilage damageis an important cause ofmusculoskeletal ...
a challenge that significantly influences the accuracy of our analysis. Imaging the sample as a function of time reveals the diffusion of the contrast agents into cartilage. Stress-relaxation measurements in indentation geometry yield the biomechanical properties of the cartilage. We hypothesize that desp...