Aripiprazole - An atypical neuroleptic drug with specific mechanism of actionOberpichlerSchwenk, H
Exact mechanism of action in schizophrenia, bipolar disorder, major depressive disorder, irritability associated with autistic disorder, Tourette's syndrome, and agitation associated with schizophrenia or bipolar mania has not been fully elucidated; may involve the drug’s activity at dopamine D2 and ...
Dosage adjustments are recommended in patients who are known CYP2D6 poor metabolizers and in patients taking concomitant CYP3A4 inhibitors or CYP2D6 inhibitors or strong CYP3A4 inducers (see Table 2). When the co-administered drug is withdrawn from the combination therapy, ABILIFY dosage should th...
A prodrug can be defined as a drug substance that needs to be converted into the pharmacologically active agent by metabolic or physicochemical transformation. After injection, aripiprazole lauroxil is converted into aripiprazole. Use of Safety and Efficacy Data from RLD (Brand Drug) Aripiprazole ...
Adding plans allows you to compare formulary status to other drugs in the same class. Log in or register for free to access formulary information Log In or RegisterMedscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional ...
Aripiprazole (Abilify). The newest, longactingaripiprazole (an arylpiperazine quinolinone derivative),appears to be partial agonist of D2receptors (i.e., itstimulates certain D2 receptors while blocking others dependingon their locations in the brain and the concentrationof drug). Bioavailability of...
When considering buying Abilify online, it is important to be aware of potential drug interactions. Abilify may interact with certain medications, and these interactions can affect the effectiveness and safety of the treatment. Here are important points to consider: ...
The drug increased DNA damage in blood, but did not show mutagenic effects, suggesting that it might affect long-term genomic stability. Keywords: antipsychotic agent; aripiprazole; locomotion; memory; genotoxic/mutagenic activities; DNA damage; lipoperoxidation Acta Pharmacologica Sinica (2011) 32: ...
Atypical antipsychotic drugs have been associated with metabolic changes that includehyperglycemia/diabetes mellitus,dyslipidemia, and weight gain. While all drugs in the class have been shown to produce some metabolic changes, each drug has its own specific risk profile. ...
The term “antibody” refers to a specific protein capable of binding an antigen or portion thereof (in accordance with this invention, capable of binding to an anti-psychotic drug or metabolite thereof). An antibody is produced in response to an immunogen which may have been introduced into a...