Serotonin syndrome induced by the combination of lamotrigine, aripiprazole and cocaineKotwal, ACutrona, S L
Aripiprazole is a second-generation antipsychotic medication that acts as a partial agonist on dopamine and serotonin receptors, making it effective for the treatment of schizophrenia, bipolar disorder, and other mental disorders. It is available in both oral and injectable formulations and has shown ...
Potential QTc-Prolonging Agents;Psycholeptics;Psychotropic Drugs;QTc Prolonging Agents;Quinolines;Quinolones;Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome;Serotonin 5-HT1 Receptor Antagonists;Serotonin 5-HT2 Receptor Antagonists;Serotonin Agents;Serotonin Receptor Antagonists;Tranquilizing Agents...
two key brain chemicals (neurotransmitters) that appear to be involved in psychiatric disorders. Dopamine has many functions including regulation of movement, memory, motivation and pleasure, while serotonin’s functions include regulation of
Aripiprazole is an atypical or second-generation antipsychotic (SGA). It balances out yourdopamineand serotonin levels. These are chemicals in yourbrainthat affect how you think, feel, and act. Your thoughts may become clearer on this drug. You may stop hearing or seeing things that aren’t ...
See also: Abilify Asimtufii, Abilify Maintena, Aristada, and Opipza How does aripiprazole work (mechanism of action)? Aripiprazole belongs to a group of medicines called second-generation (atypical) antipsychotics. It is thought to work by balancing brain chemicals called serotonin and dopamine. ...
Antipsychotic treatment, itself, however, may suppress (or partially suppress) the signs and symptoms of the syndrome and, thereby, may possibly mask the underlying process. The effect that symptomatic suppression has upon the long-term course of the syndrome is unknown. Given these considerations,...
Because he has a physical and laboratory profile that is consistent with metabolic syndrome, you consider aripiprazole monotherapy that would target both manic and psychotic symptoms.The QuestionIs aripiprazole (Abilify) effective in the treatment of manic symptoms in bipolar disorder?The AnalysisOur ...
Lawler CP, Prioleau C, Lewis MM, Mak C, Jiang D, Schetz JA, Gonzalez AM, Sibley DR, Mailman RB (1999).“Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes”.Neuropsychopharmacology 20 (6): 612–27. doi:10.1016/S0893-133X(98)0009...
serotonin, dopamine, andnoradrenalinreceptors, acting as apartial agonistat serotonin 5-HT1A anddopamine D2 receptors, and is a strong antagonist at serotonin 5-HT2A and noradrenalin α1B and α2C receptors.14It is the second in the class of partial agonist antipsychotics the first being...