详细解释: 以下为句子列表: 英文: RESULTS studies on pharmacokinetics showed that the mean residence time of HEPC-SSL in blood is 23.3h, while that of EPC-SSL is 12.0h, and the area under the curve (AUC) of concentration of HEPC-SSL is larger than that of EPC-SSL. ...
pharmacokineticsarea under the curveSynonyms AUC Definition The area under curve, AUC, corresponds to the integral of the plasma concentration versus an interval of definite time. In practice, the approximation is used: AUC = ([C] × Dt), where [C] is measured concentration and Dt is ...
Pharmacokinetics Higherarea under the curveat 15 min, 30 min, and 60 min was demonstrated in the esophageal-ligated group. Serum piroxicam levels were higher during the first 60 minutes via oral mucosal absorption than GI absorptionDiez-Ortego et al (2002). ...
BACKGROUND: This analysis was initiated to define the predictive value of the area under the curve of high-dose methotrexate (AUC(HD-MTX)) in patients with primary central nervous system lymphoma (PCNSL). PATIENTS AND METHODS: We included 55 patients with PCNSL and available pharmacokinetic (PK...
The aim of the present study was to determine whether the residual area under the curve (AUCres%; expressed as % of total value of AUC) could be used as a parameter for the qualitative evaluation of pharmacokinetic studies. We propose new criteria for the qualitative evaluation of pharmacokinet...
Area under the Moment Curve (AUMC) refers to the total area under the first moment curve, which is obtained by plotting concentration multiplied by time against time. It is a key parameter used in the calculation and analysis of drug characteristics in pharmacokinetics. ...
A polycaprolactone nanoparticle formulation of cyclosporin-a improves the prediction of area under the curve using a limited sampling strategy CyclosporinePharmacokineticsAUCDrug monitoringNanoparticlesTherapeutic monitoring of Cyclosporine (CyA) by using area under the curve (AUC) from abbreviated kinetic... ...
Optimum numerical integration methods for estimation of area-under-the-curve (AUC) and area-under-the- moment-curve (AUMC). J Pharmacokin ... RD Purves - 《Journal of Pharmacokinetics & Pharmacodynamics》 被引量: 458发表: 1992年 Optimum numerical integration methods for estimation of area-under...
ZHANG LI HONG,Xiao XJ,Y ZZ,et al.A New Method of Area under the Absorbance-Wavelength Curve for Rats Total Metabolomic Pharmacokinetics from Yangxue Injection with Multicomponents[J].Journal of Spectroscopy,2013,2013(2013):1-8.Zhang L, Xiao X,Yang Z, et al. A new method of areaunder ...
Pharmacokinetics and relative bioavailability of oral theophylline capsules There were no statistically significant differences between the bioavailability of capsules and liquid as measured by the area under the curve ( AUC ) from... LJ Lesko,AT Canada,G Eastwood,... - 《J Pharm Sci》 被引量:...