Plants, animals and fungi are all eukaryotes and have highly ordered cells. Their genetic material is packaged into a central nucleus. They also have specialized cellular components calledorganelles, each of which executes a specific task. Organelles such as the mitochondria, the rough endoplasmic ret...
This process is universal and functions in the mitochondria of all eukaryotic cells.Hans-Walter HeldtBirgit PiechullaPlant Biochemistry (Fifth Edition)HELDT, H.W.; HELDT, F. Mitochondria are the power station of the cell. In: HELDT, H.W. Plant biochemistry. San Diego: Academic, 2005a. ...
Energy fuels all of our life support activities. For energy, eukaryotic cells rely on ATP. Although the first steps of glucose metabolism happen outside the mitochondria, ATP synthesis happens within the mitochondrial matrix. On average, we produce our own body weight in ATP each day. Without ...
The mitochondria of pancreatic acinar, porcine aortic endothelial (PAE) cells, COS-7 cells and SH-SY5Y cells and neocortical astrocytes all displayed heterogeneous distributions and were of varying sizes. In general, there was a denser aggregation of mitochondria in perinuclear positions than in the ...
Diabetes increases the risk of Alzheimer’s disease (AD), and mitochondrial dysfunction is implicated in both diseases, however the impact of both diabetes and AD on brain mitochondria is not known. We measured mitochondrial DNA (mtDNA), an indicator of mitochondrial function, in frontal, parietal...
Mitochondria‐targeted GFP highlights the heterogeneity of mitochondrial shape, size and movement within living plant cells Little is known concerning the heterogeneity of mitochondrial shape, size, number, cytoplasmic distribution, and motility in planta. Ultrastructural studie... DC Logan,CJ Leaver - 《...
Cells without mitochondria are more tolerant to an anaerobic environment but are essentially irreversibly committed to death. Prevention of mitochondrial loss may be crucial for the long-term regeneration of tissues emerging from an apoptotic episode in which death was prevented by caspase blockade....
Mitochondria also contain a discreet UPR initiated when mitochondrial integrity and function are impaired. This mitochondrial UPR may also be regulated by paracrine signals with recent work identifying Wnt proteins in paracrine activation of the mitochondrial UPR57. However, a role for bioactive lipids ...
Here we have studied the intracellular movement of mitochondria and other organelles in the fungus Neurospora crassa. Four different model systems were employed: hyphae, protoplasts, a cell wallless mutant, and experimentally generated small, flattened cell fragments of the mutant cells. Organelle ...
Membrane nanotubes (MNTs) act as “highways” between cells to facilitate the transfer of multiple signals and play an important role in many diseases. Our previous work reported on the transfer of mitochondria via MNTs between cardiomyocytes (CMs) and cardiac myofibroblasts (MFs); however, the ...