Synonymous codons are used in proportion to cognate tRNA concentrations.Wenfeng QianJianRong YangNathaniel M. PearsonCalum MacleanJianzhi Zhang
The basic types of RNA present in organisms are mRNA, tRNA, rRNA and other non-coding RNAs. Their function is in the DNA transcription process. Only RNA viruses use RNA for preserving their genetic information instead of DNA. RNA composes of a chain of nucleotides connected by phosphodiester ...
occurs in the ribosomes 4. requires tRNA 5. builds strands of mRNA Is ribosomal RNA made during translation? Which of the following enclose their DNA in a nucleus? a. prokaryotes b. bacteria c. eukaryotes d. viruses Where are ribosomes locate...
It has long been known that the distribution and frequency of occurence of synonymous codons can vary greatly among different species, and that the abundance of isoaccepting tRNA species could also be very different. The interaction of these two factors
Harvard Medical School, Boston, MA, USA; 3National Institute of Biological Sciences, Beijing, China; 4Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA, USA mRNAs containing premature termination codons (PTCs) are known to be degraded via nonsense-mediated mRNA decay...
mRNAs containing premature termination codons (PTCs) are rapidly degraded through nonsense-mediated mRNA decay (NMD). However, some PTC-containing mRNAs evade NMD, and might generate mutant proteins responsible for various diseases, including cancers. Us
Transcription is the creation of a strand of mRNA from a DNA template, carrying the same instructions (i.e., genetic code) for making a particular protein as the template does. The process occurs in the cell nucleus, where DNA is located. When a double-stranded DNA molecule separates into...
In these cases, however, the initial amino acid that is incorporated appears to be methionine, apparently because these non-AUG codons can still form weak base pairs with the initiator Met-tRNAMet (26, 28). A clear illustration of these issues occurs with the Gag protein of murine leukemia ...
The -1 programmed ribosomal frameshifts (PRF), which are used by many viruses, occur at a heptanucleotide slippery sequence and are currently thought to involve the tRNAs interacting with the ribosomal P- and A-site codons. We investigated here whether the tRNA occupying the ribosomal E site ...
What are the four nitrogenous bases found in RNA? What is a RNA virus genome? How does RNA structure differ from DNA structure? Why is it called a transfer RNA? Where is transfer RNA located? What is the shape of RNA? How many codons specify the twenty types of amino acids?