AR-M1896是一种具有高度选择性的GalR2(半乳糖凝集素受体2)激动剂,它在生物医学研究中展现出了独特的价值和潜力。具体而言,AR-M1896对大鼠GalR2的结合亲和力极强,其IC50(半抑制浓度)值达到了1.76 nM,这一数据充分表明了它与GalR2之间的高效且特异性的相互作用。 GalR2作为半乳糖凝集素受体家族的一员,在调节多...
In the forced swim test, injection of AR-M1896 into the lateral ventricle decreased immobility time and increased climbing time in the CUMS rats; but injection of artificial cerebrospinal fluid did not change the immobility time and climbing time in the CUMS rats. All those data suggest that ...
P3-299: Galanin and its agonist AR-M1896 protects the SN56 cholinergic cell line against beta amyloid 25-35 toxicityMultiple sclerosis failure of re-myelination processes. Alzheimer diseasedoi:10.1016/j.jalz.2008.05.1867Calza'LauraPirondiStefania...
急性心肌梗死研究:在急性心肌梗死的研究中,AR-M1896作为GalR2的选择性激动剂,为科学家们提供了一种有力的工具来探索GalR2在心脏保护中的作用机制。通过激活GalR2,AR-M1896可能能够调节心肌细胞的存活、减少心肌梗死的面积,并改善心脏功能。 神经性疼痛研究:AR-M1896在神经性疼痛的研究中也展现出了广阔的应用前景。