Ag; Abpp; Adap; Cvap; Abeta; betaApp; E030013M08Rik 染色体位置 16 NCBI ID 11820 MGI ID 88059 Ensembl ID ENSMUSG00000022892 Pubmed App 人类同源基因 APP品系描述 将小鼠App基因全部或者部分替换为人源AppNL-G-F,从而表达人或人鼠嵌合AppNL-G-F蛋白,取代小鼠内源App蛋白的表达。 应用领域:老年痴...
APP 品系描述 将小鼠App基因全部或者部分替换为人源AppNL-G-F,从而表达人或人鼠嵌合AppNL-G-F蛋白,取代小鼠内源App蛋白的表达。 应用领域:老年痴呆AD相关人源化小鼠模型 *使用本品系发表的文献需注明: hAppNL-G-F mice (Cat. NO. NM-HU-2000088) were purchased from Shanghai Model Organisms Center, In...
Groups of Appwt and AppNL-G-F mice were also treated with the vehicles. Cognitive tests The Novel Object Recognition (NOR) test was performed following the protocol described in [32]. On the first day, the habituation session, mice were placed in the empty box and allowed to explore for...
Groups of Appwt and AppNL-G-F mice were also treated with the vehicles. Cognitive tests The Novel Object Recognition (NOR) test was performed following the protocol described in [32]. On the first day, the habituation session, mice were placed in the empty box and allowed to explore for...
House dust mite-induced asthma exacerbates Alzheimer’s disease changes in the brain of the AppNL-G-F mouse model of disease Brain, Behavior, and Immunity, Volume 121, October 2024, Pages 365-383 Bijayani Sahu, Suba Nookala, Angela M. Floden, Nilesh S. Ambhore, Venkatachalem Sathish, Mari...
we investigated the relationships between the levels of amyloid-β oligomers, amyloid-β plaques, glial activation and markers related to neurodegeneration in the AppNL-G-F triple mutation mouse line and in a knock-in line homozygous for the common human amyloid precursor protein (Apphu mouse). ...
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