The present invention relates to the discovery of a toxin-antitoxin system in opportunistic human pathogenand to the applications of this discovery including the stabilization of plasmids useful in the field of recombinant DNA technology for production of genes and their products. The Phd-like (...
The present invention relates to the discovery of a toxin-antitoxin system in opportunistic human pathogen and to the applications of this discovery including the stabilization of plasmids useful in the field of recombinant DNA technology for production of genes and their products. The Phd-like (prev...
To overcome this, the bacteria have evolved with the production of a molecule, referred to as antitoxin, to negate the deleterious effect of the toxin against itself. The toxin and antitoxins are encoded by a two-component toxin-antitoxin (TA) system. The antitoxin, a protein or RNA, ...
Toxin-antitoxin systems and their medical applications: current status and future perspective Almost all bacteria synthesize two types of toxins鈥攐ne for its survival by regulating different cellular processes and another as a strategy to interact ... A Srivastava,S Pati,H Kaushik,... - 《Applied...
Other bacterial ense systems that have been studied or discovered by NGS include the toxin/anti-toxin, antigen, novel restriction-modification, and DNA phosphorathioation systems as well as those involved with infection-induced dormancy or programmed cell death [192]. Genomic sequencing also has ...
butyricum, akin to previously described toxin-antitoxin systems (Jurenas et al., 2022), which could facilitate the development of stable expression vectors in other Clostridium spp. 3.5. Secreted expression of Cel9M via pCB102 confers stable endoglucanase activity To explore the potential industrial ...
the pH-responsive molecules eliminated the toxin significantly faster than the conventional molecules. Recycling and sweeping antibodies theoretically can remove antigens out of circulation even if they do not neutralize them in in-vitro assays. Thus, they can be used as efficient antitoxins when a ...
other side, it will overview the potentials of the different classes of single-domain antibodies that developed massively in the last two years, such as immunoaffinity, assisted crystallography, protein aggregation and activity tuning, and toxin inactivation, for which a systematic update is now ...
However, many of the extra-intestinal serovars ofSalmonellado not encode SPI-7 or the typhoid toxin. Therefore, alternative mechanisms for the systemic dissemination are likely to have evolved in these serovars. This reflects the convergent evolution to an extra-intestinal lifestyle reflected in the...
This invention provides magnetic nanoparticles, which when placed in a magnetic field are selectively heated at a certain frequency of the magnetic field, as a function of their siz