What is Apolipoprotein B? ApoB reference rangeNormal ApoB levelsHigh ApoB levelsLow ApoB levelsHow are ApoB and LDL cholesterol levels related?Do genetics influence ApoB levels?How can you measure your ApoB levels? Get your personal health analytics dashboardHow can you lower ApoB levels...
B Teng,C Burant,N Davidson - 《Science》 被引量: 1307发表: 1993年 Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production How omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) lower plasma lipid levels is incompletely understood. We previously...
How to Cite Holewijn, S., Den Heijer, M., Swinkels, D. W., H Stalenhoef, A. F. and De Graaf, J. (2010), Apolipoprotein B, non-HDL cholesterol and LDL cholesterol for identifying individuals at increased cardiovascular risk. Journal of Internal Medicine, 268: 567–577. doi: 10.1111...
If HMGCoA reductase inhibitors such as simvastatin lowered LDL mainly by up-regulating LDL-receptor mediated clearance, they should decrease the overall binding affinity of LDL from an FDB heterozygote by selectively decreasing LDL bearing normal apo B. We compared how LDL from FDB heterozygotes ...
Sypniewska G, Bergmann K, Krintus M, Kozinski M, Kubica J. How do apolipoproteins Apo B and Apo A-I perform in patients with acute coronary syndromes. Journal of Medical Biochemistry 2011; 30: 237-43.Sypniewska G, Bergmann K, Krintus M, Koziński M, Kubica J. How do ...
In this context, given the atherogenicity of glycated apolipoprotein B100 (glycApoB), the aim of the present study was to assess how bariatric surgery influences glycApoB and to explore the relation between changes in glycApoB concentration and how these relate to changes in glycaemic and lipid ...
We also discuss how APOE can be targeted for AD therapy using a precision medicine approach. Key points The apolipoprotein E (APOE) gene has three major allelic variants, APOE*ε2, APOE*ε3 and APOE*ε4; APOE*ε4 is associated with an increased risk and lower age of onset of Alzheimer...
Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype. J Nutr 2010; 140: 278–284. 19 Cohn LD, Becker BJ. How meta-analysis increases statistical power. Psychol Methods 2003; 8: 243–253. 20 Higgins JP, Thompson SG. Quantifying ...
However, it is still unclear how the liver regulates the triglyceride (TG) content of VLDL particles to produce large VLDL1 or small VLDL2. VLDL assembly is thought to involve at least two steps in which nascent VLDL particles are formed and then TG is added, resulting in larger particles ...
The seeded growth of pathogenic protein aggregates underlies the pathogenesis of Alzheimer’s disease (AD), but how this pathological cascade is initiated is not fully understood. Sporadic AD is linked genetically to apolipoprotein E (APOE) and other genes expressed in microglia related to immune, ...