Posttranslational modification (PTM) of NLRP3. NLRP3 activity is controlled by various PTMs, including the ubiquitination of lysine residues and the phosphorylation of serine and tyrosine residues, which either enhance (top panel) or reduce (lower panel) NLRP3 assembly and activity. PTMs are regu...
HDL is actually more complex than we once thought. Rather than being a single kind of particle, HDL is is now considered a family of different particles. All HDL contains lipids (fats), cholesterol and proteins (called apolipoproteins), but some types of HDL are spherical while others are ...
Results from the Québec Cardiovascular Study have indicated that individuals displaying three of the numerous features of insulin resistance (elevated plasma insulin and apolipoprotein B concentrations and small, dense LDL particles) showeda remarkable increase in CHD risk. Our data suggest that the incr...
high density lipoprotein (HDL or good cholesterol) and apolipoprotein B, a specific protein found in bad cholesterol that clogs arteries, they concluded that just substituting one or two meat or dairy meals with non-animal protein slashed the risk of heart disease. High-fibre...
More than one-third of American adults are obese and statistics are similar worldwide. Caloric intake and diet composition have large and lasting effects on cognition and emotion, especially during critical periods in development, but the neural mechanis
Understanding changes to apolipoprotein transcripts is complicated since mice and humans metabolize cholesterol and triacylglycerol differently (e.g., mice carry most of their cholesterol in HDL particles) and apolipoprotein polymorphisms have large impacts on cholesterol metabolism. FUNG decreased apoc1 (...
reuteri NCIMB 30242 per day for nine weeks reduced LDL-cholesterol levels, as well as hs-CRP, apolipoprotein B-100 (apoB-100) (a lipid fraction associated with atherosclerosis development), and fibrinogen levels, and increased vitamin D levels.158,159 Similarly, a yogurt providing 1.4 billion ...
husk fiber supplementation to the diets rich in soybean or coconut oil: hypercholesterolemic effect in healthy humans.International Journal of Food Sciences and Nutrition,March1996.In this study, investigators found that the coconut oil diet increased serum cholesterol, LDL, and apolipo...
I could go on and on, but you get the idea. On a side note, I train a podiatrist. I asked him what percentage of lower extremity amputations he does are a result of uncontrolled diabetes. Didn’t take him long to answer.Eighty to eighty-five percent. That’s a lot. ...
Cooking the same foods using lower temperatures, high moisture, and/or pre-exposure to an acidified environment will limit new AGEs formation.2, 68 Regrettably, the toxic effects ofhigh-temperaturecooking and food processing are still not accepted health considerations, despite irrefutable evidence we...