High apolipoprotein B, low apolipo- protein A-I, and improvement in the prediction of fatal myocardial infarc- tion (AMORIS study): a prospective study. Lancet. 2001;358:2026-33.Walldius G,Jungner I,Holme I,et al.High apolipoprotein B, low apolipoprotein A-I, and improvement in the ...
Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor Article 11 December 2024 Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles Article Open access 15 January 2020 Conformational changes in Apolipoprotein N-acyltransferase (Lnt...
(HRs), adjusted for several conventional factors, were calculated for 1-SD higher values: 0.52 loge triglyceride, 15 mg/dL high-density lipoprotein cholesterol (HDL-C), 43 mg/dL non–HDL-C, 29 mg/dL apolipoprotein AI, 29 mg/dL apolipoprotein B, and 33 mg/dL directly measured low-...
Apolipoprotein (Apo) B provides a measure of atherogenic particles in blood, a predictor for coronary heart disease (CHD) events. Reducing low-density lipoprotein cholesterol (LDL-C) to current goals may still leave an excess of atherogenic lipoproteins. A study of predominantly white high-risk ...
These increases in ApoB and small LDL-C particles magnify the coronary risk byfive folds.10,11,12 Consequently, this implies that low saturated fat, high carbohydrate diets should not bethe only dietary modification recommended in the prevention of coronary artery disease. In the presentcase ...
Serum-containing medium was then replaced with neurobasal medium containing N2 supplement and nerve growth factor (100 ng/ml) to stimulate differentiation overnight. Cell-secreted Aβ was obtained from PDAPP primary neuronal cultures that contained ∼60% Aβ42. This high Aβ42: Aβ40 ratio is...
This article reviews the evidence showing that apolipoprotein (apo) B and A-1 are superior to the conventional cholesterol indices as analytes in laboratory practice, indices of the lipoprotein-related risk for vascular disease, and measures of the adequacy of low-density lipoprotein-lowering therapy...
between baseline and on-study apolipoproteins (apo) A-1 and B and lipoprotein(a) [Lp(a)] levels and the development of subsequent cardiovascular (CV) events in the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes)...
Human Apolipoprotein B-100 are the primary apolipoproteins of chylomicrons and low-density lipoproteins (LDL), which are responsible for carrying cholesterol to tissues. While it is unclear exactly what functional role APOB plays in LDL, it is the primary apolipoprotein component and is absolutely ...
Scavenger receptor class B type I (SR-BI) in pig enterocytes: trafficking from the brush border to lipid droplets during fat absorption Scavenger receptor class B type I (SR-BI) is known to mediate cellular uptake of cholesterol from high density lipoprotein particles and is particularly ab......