Apolipoprotein B and non-high-density lipoprotein cholesterol reveal a high atherogenicity in individuals with type 2 diabetes and controlled low-density lipoprotein-cholesterolDyslipidemiaApoBLDL-cCVDCV riskNon-HDL cholesterolT2DMComparison of clinical and laboratory variables between type 2 diabetes ...
This study sought to examine the relationship between baseline and on-study apolipoproteins (apo) A-1 and B and lipoprotein(a) [Lp(a)] levels and the development of subsequent cardiovascular (CV) events in the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Trigl...
High-density lipoproteins (HDLs) mediate cholesterol transport and protection from cardiovascular disease. Although synthetic HDLs have been studied for 30 years, the structures of human plasma–derived HDL and its major protein apolipoprotein apoA-I are unknown. We separated normal human HDL into five...
high-density lipoprotein cholesterol HOMA-IR, homeostasis index insulin resistance Lp, lipoprotein Because low HDL-C is a known predictor of cardiovascular disease (1,2) and high levels are protective (3) in adult popu- lations, it follows that low levels in childhood may increase cardiovascular ...
The kinetic parameters of high-density lipoprotein (HDL) and its major apolipoproteins (Apo) AI and Apo All were studied in 2 patients with moderate and severe proteinuria and 2 normal controls after intravenous injection of autologous <sup>125</sup>I-HDL. The fractional catabolic rates (FCR)...
Studies of Apolipoprotein B And Lipoprotein(a) in Transgenic Mice A clone containing the entire human apoB gene was isolated and used to create multiple lines of mice expressing high levels of human apoB. The lipoproteins of the human apoB transgenic animals differed from control mice due to ...
Apolipoprotein A-I and apolipoprotein B were assayed by immunoturbidimetry (Behring Werke A. G., Marburg, Germany). LpA-I, Lp[a], and apolipoprotein C-III were assayed by electroimmunodiffusion (Sebia, Issyles-Moulineaux, France). Plasma and buccal mucosal cell β-C was extracted twice with...
Thematic review series: The Pathogenesis of Atherosclerosis The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL high density lipoproteinarachidonic acidapolipoprotein A-I mimetic peptidesreverse cholesterol transportFor more than two decades, there has been continuing ... M...
Our present finding may provide a plausible explanation for the contradictory findings about the acute phase protein nature of Lp(a). 展开 关键词: apolipoprotein(a)/IL-6/lipoprotein(a)/Lp(a)/multiple myeloma DOI: 10.1006/cyto.2002.1044 被引量: 9 ...
Age and Cardiovascular Risk Attributable to Apolipoprotein B, Low‐Density Lipoprotein Cholesterol or Non‐High‐Density Lipoprotein Cholesterol Background Higher concentrations of the apolipoprotein B (apoB) lipoproteins increase the risk of cardiovascular disease. However, whether the risk associa... AD ...