Amr S, Chowdhry P, Hamosh P, Hamosh M 1988 Low levelsof apolipoprotein A-l are not contributors to the low lecithin: cholesterol acyl transferase activity in premature newborn infants. Pediatr Res 24:191-193Amr S, Chowdhry P, Hamosh P, Hamosh M. Low levels of apolipoprotein A1 are not...
中文名称载脂蛋白a1抗体 别名Apo-AI; ApoA I; ApoA-I; APOA1_HUMAN; Apolipoprotein A-I(1-242); Apolipoprotein A1; Apolipoprotein A 1; Apolipoprotein AI; Apolipoprotein A I; Brp14; Ltw1; Lvtw1; Sep1; Sep2. 研究领域心血管 神经生物学 信号转导 脂蛋白 新陈代谢 ...
lecithin cholesterol acyl transferase which converts cholesterol to cholesteryl esters. During lypolysis in the peripheral tissue, Apo A1 can also play a role as an acceptor for surface components of very low density lipoproteins and chylomicrons. The gene encoding Apo A1 is found on chromosome 11...
11.Should the apolipoprotein B/A1 ratio become the routine lipid measurement for cardiovascular risk stratification? 是否载脂蛋白B/A1比值能作为常规脂质测量用来进行心血管危险分层? 12.Mutations in the apolipoprotein E gene (APOE) are one of the strongest risk factors for late-onset Alzheimer’s. ...
作者: None 摘要: Summary Cell culture and mouse studies suggest that APOA1 peptide mimetics could help treat ovarian cancer. Low APOA1 serum levels are prognostic for early stage ovarian cancer.. 2010 Nature Publishing Group DOI: 10.1038/scibx.2010.1324 年份: 2010 收藏...
分子名:APOA1, apolipoprotein A1 基因家族:Apolipoproteins 全称:apolipoprotein A-I APOA1 分子靶点综述 载脂蛋白A1 (Apo A1)是血浆中高密度脂蛋白(HDL)的主要蛋白成分。小肠上皮细胞分泌的乳糜微粒也包含Apo A1,但是它很快就转移到血液的HDL中。该蛋白在脂质代谢中有特定作用,它促进脂肪流出,包括将组织中的胆固...
Recent studies have reported of an association between high serum apolipoprotein A1 (APOA1) levels and favorable prognosis in several malignancies, while the significance of apolipoprotein B (APOB) in cancer is less well-known. In this study, we analyzed
Heterodimer of LXR/RXR interacts with DNA elements near the promotor of ABCA1, ABCG1, and APOE and upregulates their expression. When astrocytes release ApoE, it binds to the lipids (cholesterol and phospholipids through the ABCA1 and ABCG1 transporters) and forms HDL-like particles, which ...
Background A low high?density lipoprotein cholesterol (HDL?C) to apolipoprotein A?I (apoA?I) ratio which reflects a small HDL?C particle size is emerging as an important predictor of cardiovascular risks. This study aimed to determine the association of HDL?C/apoA?I ratio with the severity ...
The apoA-I-mediated increase in glucose uptake by HSKMCs was dependent on phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/Akt, the ATP binding cassette transporter A1 (ABCA1) and scavenger receptor class B type I (SR-B1). Taken together, these results establish that apoA-I increases ...