AlphaFold2-Based Characterization of Apo and Holo Protein Structures and Conformational Ensembles Using Randomized Alanine Sequence Scanning Adaptation: Ca... AlphaFold2-Based Characterization of Apo and Holo Protein Structures and Conformational Ensembles Using Randomized Alanine Sequence Scanning Adaptation: ...
Again, there are differences between the apo and the holo forms. The results are intriguing in suggesting that the presence or absence of ligand has an impact on the types of coupled motions that are present between protein and water. For example, the apo form has the weakest degree of ...
比较分析: 顶行比较了 MDapo（红色）、EDES3w（蓝色）、EDES4w（绿色）分布与 MDholo 分布（深灰色）。分布以实心点和透明表面展示。空蛋白和配体结合蛋白结构分别以红色和黑色球体表示。分布覆盖: 底行展示了 MDapo（红色）、EDES3w（蓝色）、EDES4w（绿色）分布与 MDholo 分布（深灰色）的重叠。还报告了重叠...
The protein was purified 184-fold over its concentration in plasma. When the plasma was labelled with a tracer concentration of [3H]calcidiol, it was apparent that holo- and apo-DBP did not co-chromatograph on chromatofocusing. The separation of these two forms of DBP on chromatofocusing was...
MD snapshots. Figures 2 and 3 display the results of such analyses and show that the b-barrel struc- tures composed of the ten strands b A -b J and the two helices a I -a II remain largely intact for the entire simulation. The holo-protein appears to be slightly...
比较分析: 顶行比较了 MDapo(红色)、EDES3w(蓝色)、EDES4w(绿色)分布与 MDholo 分布(深灰色)。分布以实心点和透明表面展示。空蛋白和配体结合蛋白结构分别以红色和黑色球体表示。 分布覆盖: 底行展示了 MDapo(红色)、EDES3w(蓝色)、EDES4w(绿色)分布与 MDholo 分布(深灰色)的重叠。还报告了重叠分布的体积...
align both apo- and holo-proteinsto the query holo protein Given the apo form of a protein(a protein structurewithout any ligands): findall other forms of that protein that bind at least one ligand (holo-proteins). findall other unbound forms of that protein (apo-proteins) that completely...
The net rate of holo-heme protein formation should be given by the difference in the rates of these processes: 31.1Rnet,holoMb=kheme•KUN1+KUN−kdegrade•11+KUN where R is the rate of holoprotein formation, KUN is the folding equilibrium constant (unfolded, U, to native, N, ...
Bovine Transferrin(牛转铁蛋白)以高纯度、热处理、冻干粉状态提供,并有脱铁(apo)或饱和铁(holo)两种形式。 饱和铁转铁蛋白(holo transferrin)持续地释放铁离子,并形成脱铁转铁蛋白(apo transferrin)。需要根据具体培养条件选择,如DMEM/F12培养基中含有高浓度的铁,一般选择脱铁转铁蛋白。
Bovine Transferrin (HOLO)牛饱和铁转铁蛋白 100mg 956 J2315 Bovine Transferrin (APO)牛脱铁转铁蛋白 100mg 956 产品简介: 转铁蛋白(Transferrin,TRF,Tf)又称铁传递蛋白、运铁蛋白,是脊椎动物血浆中主要的糖蛋白。Transferrin不仅直接参与铁离子的运输和代谢,还具有许多生理生化功能,如抗菌活性、参与免疫系统的细胞...