ABSTRACT. A total of 745 patients with cytopenia (aplastic anemia 157, hemolytic anemia 101, agranulocytosis 136, thrombocytopenia 351) were diagnosed during a 5-year period in a health care region comprising 16% of the Swedish population. The total incidence was for aplastic anemia 24.6, ...
Both increased graft rejection and increased graft vs host disease (GVHD) remain obstacles to success for unrelated donor (URD) BMT for patients with SAA. Partial T cell depletion (PTCD) may decrease the risk of severe GVHD, while still maintaining suffi
Although paroxysmal nocturnal hemoglobinuria (PNH) is a clinically heterogeneous disease, it often occurs in patients with underlying bone marrow failure (BMF), most commonly in those with aplastic anemia (AA),1, 2 and concurrent AA can be associated with poorer outcomes in patients with PNH.3 ...
Autoimmune hemolytic anemia, autoimmune neutropenia and aplastic anemia in the elderly - ScienceDirectWilma Barcellini aBruno Fattizzo bAgostino Cortelezzi bEuropean Journal of Internal Medicine
Reviews the clinical courses of children less than or equal to 16 years of age with hereditary hemolytic anemias who were admitted to the University of Mississippi Medical Center for aplastic crisis. The conclusion that erythroid (but not other) blood cell lines are helpful in establishing a ...
1 , 2 Even if the clinical manifestations may change over time, 3 most, if not all PNH patients, have a degree of aplastic anemia (AA) with or without significant hemolysis that may require a treatment according to its severity. While classical hemolytic PNH patients without significant ...
newly diagnosed MAA (62% vs. 12%, p=0.003). Eight patients developed MDS/AML with the similar 12-year cumulative incidence in both groups (30% vs. 31%, p=1.0).Late events also included rectal cancer (n=1) and hemolytic PNH (n=6). Ten patients died due to cytopenia complications (...
APLASTIC anemiaCORD bloodTOTAL body irradiationGRAFT rejectionTRANSPLANTATION of organs, tissues, etc.AUTOIMMUNE hemolytic anemiaHaplo‐identical donors have been increasingly used as an alternative source of stem cells in patients with severe aplastic anemia in need of an allogeneic transplantation but lack...