Acquired aplastic anemia (AA) is characterized by low peripheral blood counts and decreased bone marrow cellularity. The cause of AA is unknown in the majority of cases, hence the term idiopathic aplastic anemia. The major pathophysiologic mechanism implicated in acquired AA is autoimmune dysregulation...
that includes the term aplastic. aplastic anemia noun : anemia that is characterized by defective function of the blood-forming organs (such as the bone marrow) and is caused by toxic agents (such as chemicals or X-rays) or is idiopathic in origin See the full definition Word of the Day...
Aplastic Anemia Aplastic anemia is characterized by pancytopenia on peripheral smear. The criteria for severe aplastic anemia includes a bone marrow biopsy showing <50% normal cellularity in which fewer than 30% of the cells are hematopoietic and at least two of the following are present: absolute...
Aplastic (hypoplastic) anemia is characterized by pancytopenia caused by hypoplasia of the marrow in the absence of an abnormal marrow infiltrate or increase in reticulin. The inherited forms of aplastic anemia may be associated with other somatic congenital defects, as in the Fanconi syndrome, an ...
Aplastic anemia (AA) is a rare disease characterized by pancytopenia and marrow parenchyma that is lacking hematopoietic elements. This chapter summarizes the results of marrow hematopoietic cell transplantation (HCT) for severe AA over the past 40 years. Early reports of marrow HCT for SAA ...
Aplastic anemia is characterized by decreased bone marrow function with inadequate production of erythrocytes, granulocytes, and platelets. Marrow failure may be caused by absence of or defects in hematopoietic stem cells, abnormalities of the bone marrow microenvironment, ineffective cell-to-cell interacti...
Aplastic anemia (AA) is a kind of bone marrow failure (BMF) characterized by pancytopenia with hypoplasia/aplasia of bone marrow. Immunosuppressive therapy and bone marrow transplantation are effective methods to treat severe aplastic anemia. However, the efficacy is limited by complications and the ...
Aplastic anemia (AA) is a rare immune-mediated hematopoietic disorder characterized by weakened proliferation of bone marrow hematopoietic cells, reduced peripheral whole blood cells, and immune dysfunction1. The main clinical manifestations consist of different degrees of anemia, hemorrhage and infection ...
Aplastic anemia is characterized by diminished or absent hematopoietic precursors in the bone marrow, most often due to injury to the pluripotent stem cell. In Pakistan, Aplastic Anemia is not uncommon and allogeneic hematopoietic stem cell transplant remains the only curative option in these patients...
Aplastic anemia (AA) is a syndrome characterized by pancytopenia and bone marrow hypoplasia. Although the etiology remains unclear, the immune destruction of hematopoietic stem cells has been considered the most important mechanism of bone marrow failure in AA [1]. One important finding supporting the...