apicoplast 质体样细胞器 顶复合器门的原生动物 (Apicomplexanprotozoa)含有一个高度退化的质体样 (plastid like)细胞器 ,定名为apicoplast。来自apicoplast的clpC基因和它在其他质体和细菌中的同源物用来重建apicoplast的系统发育史。使用邻接法 (Neighbor Joining)、最小进化法 (MinimumEvolution)、最大简约...
An apicoplast is an acquired ∼35 kb DNA-containing plastid type body (from endosymbiosis by green algae) in several parasites (e.g., Toxoplasma, Plasmodium). The Plasmodium falciparum apicoplast contains about 466 proteins, which are mainly nuclear encoded and imported with the aid of signal ...
顶复合器门的原生动物(Apicomplexanprotozoa)含有一个高度退化的质体样(plastidlike)细胞器,定名为apicopl...
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顶复合器门的原生动物 (Apicomplexanprotozoa)含有一个高度退化的质体样 (plastid like)细胞器 ,定名为apicoplast。来自apicoplast的clpC基因和它在其他质体和细菌中的同源物用来重建apicoplast的系统发育史。使用邻接法 (Neighbor Joining)、最小进化法 (MinimumEvolution)、最大简约法 (MaximumParsimony)和最大似然法(...
The full nuclear genome of the malaria parasite yielded the first clues to the apicoplast raison d’être, showing that apicoplasts make essential cellular building blocks such as fatty acids, isoprenoid precursors, haem and iron/sulphur clusters. Because apicoplasts have the same ancestry, the way...
the apicoplast ofT. gondiiandPlasmodiumspp. harbours a number of common pathways; namely a fatty-acid type II (FASII), haem-, isoprenoid- (IPP),lipoic acidand iron–sulfur [Fe–S] clusterbiosynthesis[20]. In contrast inTheileriaandBabesiaspecies, the organelles only hosts theisoprenoidand Fe–...
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The apicoplast is indispensable for parasite replication and continued infection of host cells. Investigating proteins that are produced by, or function in, the apicoplast could generate answers to the questions surrounding the function of the apicoplast. Apicoplast metabolic networks The networks of ...
The apicoplast, a relic plastid organelle derived from secondary endosymbiosis, is crucial for many medically relevant Apicomplexa. While it no longer performs photosynthesis, the organelle retains several essential metabolic pathways. In this study, we