van Wyk, R., et al., Somatic mutations of the APC, KRAS, and TP53 genes in nonpolypoid colorectal adenomas. Genes Chromosomes Cancer, 2000. 27(2): p. 202-8. :van Wyk R., Slezak P, Hayes VM et al. Somatic mutations of the APC, KRAS, and TP53 genes in nonpolypoid colorectal...
El gen más frecuentemente mutado fue APC (15.3%), seguido de KRAS (10.1%) y TP53 (5.1%). Las muestras de CCR presentaron una frecuencia de mutaciones del 46,7% y las CE del 13.3% (p = 0.006). No se encontraron mutaciones simultáneas en los 3 genes. En solo 6 muestras de ...
Conclusion: As FOLFIRI+Bevacizumab has recently also been associated with sustained complete remission in a APC/TP53/KRAS triple-mutated patient, these driver genes should be tested and monitored in a more in-depth manner in future patients. Patients with metastatic disease should be monitored more ...
Indonesian Genomic Landscape of Pathogenic Mutation of APC, KRAS, TP53, PIK3CA, and MLH1 in Colorectal Cancerdoi:10.21203/rs.3.rs-900277/v1Vania MarbunToar Jean Maurice LalisangLinda Erlina
128 use of a biochip assaying 28 mutations in the kras, braf, tp53, and apc genes for detection of colorectal neoplasiadoi:10.1016/S1359-6349(10)70936-8D. HughesC. O'MorainN. LeeL. KelleyM. EbertElsevier LtdEuropean Journal of Cancer Supplements...
METHODS OF DETECTING CANCER COMPRISING SCREENING FOR MUTATIONS IN THE APC, EGFR, KRAS, PTEN AND TP53 GENESMethods and compositions involving molecular markers for the detection and\ncharacterization of cancer in a\npatient are provided.LANCHBURY, JERRY...
128 Use of a biochip assaying 28 mutations in the KRAS, BRAF, TP53, and APC genes for detection of colorectal neoplasiaHughesD.OMorainC.LeeN.KelleyL.McMurrayH.ingentaconnectEuropean Journal of Cancer Supplement