Single cell analysis of mutations in the APC gene. Mayer Veronika,Schoen Ulrike,Holinski-Feder Elke,Koehler Udo,Thalhammer Stefan. Fetal Diagnosis and Therapy . 2009Thalhammer S (2009) Single cell analysis of mutations in the APC gene. Fetal Diagn Ther 26 - Mayer, Schoen, et al. () ...
在流式细胞仪中使用P..流式细胞术和荧光激活细胞分选(FACS)使细胞生物学中的分析达到了前所未有的水平。利用这些工具,可以针对特定的,具有生物学意义的特征,逐个细胞地筛选和表征整个细胞群。确定给定群体中活细胞的百分比,或量
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics 在复杂疾病的全基因组关联研究中发现的遗传风险变异主要是非编码。将这些风险变异转化为机制见解需要详细的疾病相关细胞类型的基因调控图。在这里,作者结合了两种方法:使用520580个样品的1型糖尿病(T1D)的全基因组关联研究,以及使用单核测定...
n = 2 single-cell Apc−/− KO clones per Wnt antagonist. i, MFI for TOP-GFP expression in the presence of Wnt3a and Apc−/− KO CM (P = 0.3606, one-way ANOVA, between all Apc-mutant conditions). Data are mean ± s.e.m., each dot represents a single-cell Apc−/−...
This 1C2 antibody has been tested by flow cytometric analysis of mouse platelets. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be...
single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK ...
decr eas e in the numb er of single cells by using t he formula [ ( N0 一Ni) /N【 】J/l oo.w here N【 】is the n umb er of sin gle cell s at t im e 0 ,an d N .is t h e n u mb er o f sin gle cells
The diversity of APC in use partly reflects the fact that no single technique of Ag presentation is ideal. For the clinician and laboratory worker alike the field can seem illogical and confusing. In this review we outline the functional requirements of APC for the induction of T cells, ...
c Translocation distance of whole photoactivated region towards the cell body was measured (n = 21 dendrites control shRNA, n = 26 dendrites APC2 shRNA, N = 3, Two-Way ANOVA, Tukey post-hoc). d Distance of microtubule bundles sliding out of the photoactivated region both ...
One does not often look to analytic cubism for insights into the control of the cell cycle, but Pablo Picasso beautifully encapsulated the fundamentals when he said that "every act of creation is, first of all, an act of destruction". The rapid destruction of specific cell cycle regulators at...