Apathy and impulsivity are debilitating conditions associated with many neuropsychiatric conditions, and expressed to variable degrees in healthy people. While some theories suggest that they lie at different ends of a continuum, others suggest their possible co-existence. Surprisingly little is known, ho...
The most commonly implicated areas in effort-based decision-making are the ventral striatum (VS), the AI, the DLPFC, as well as interconnected portions of the dACC (Apps and Ramnani, 2014; Chong et al., 2017; Croxson et al., 2009; Dixon and Christoff, 2014; Kurniawan et al., 2013; ...
Conclusion:It is important for clinicians to know that most people with dementia are not apathetic, though it is common. Most of those with significant symptoms of apathy improve without specific treatments, although some also relapse, meaning that intervention may not be needed. Future research ...
It can be considered as a separate syndrome or as a symptom of other disorders e.g. depression. Almost twenty per cent of community-dwelling elderly persons who are free of dementia and depression have symptoms of apathy24. Apathy is associated with a higher risk of functional impairment, ...
Behavioural disorders and psychological symptoms of Dementia (BPSD) are commonly observed in Alzheimer's disease (AD), and strongly contribute to increasing patients' disability. Using voxel-lesion-symptom mapping (VLSM), we investigated the impact of white matter lesions (WMLs) on the severity of...