Taken together, it is clear from neuroimaging studies across several different disorders that apathy is most commonly associated with changes in the metabolic, gross and functional anatomy of fronto-striatal circuits. Moreover, the most common deficit appears to be to VS, and to portions of interco...
While apathy and depression may show matching characteristics, depression is a mental health condition, and apathy is often a symptom of another issue. Potential causes of apathy include dementia, schizophrenia, or stroke, for example. A licensed online
Apathy and impulsivity are debilitating conditions associated with many neuropsychiatric conditions, and expressed to variable degrees in healthy people. While some theories suggest that they lie at different ends of a continuum, others suggest their possible co-existence. Surprisingly little is known, ho...
After a brief introduction on the phenomenology of apathy and the questions raised by some clinical and imaging studies, we will review and discuss recent advances in the development of rodent models of PD-related neuropsychiatric symptoms. Most of these animal lesion studies point toward the critica...
Behavioural disorders and psychological symptoms of Dementia (BPSD) are commonly observed in Alzheimer's disease (AD), and strongly contribute to increasing patients' disability. Using voxel-lesion-symptom mapping (VLSM), we investigated the impact of white matter lesions (WMLs) on the severity of...
Without a gold standard for defining and measuring apathy, the availability of empirically sound measures is imperative. This paper provides a psychometric review of the most commonly used apathy measures and provides recommendations for use and further research. Pertinent literature databases ...
In short, apathy is a symptom that can be observed in depression but may also occur without depression and, when both are present, they may be clinically and anatomically independent [19,21,24]. According to Marin [25], apathy is a lack of motivation, characterized by diminished goal-direct...