NES, normalized enrichment score. k The most enriched GO terms in significantly expressed genes in the Csrp1KO embryoid bodies. The GO enrichment analysis used the two-sided Fisher’s exact test with the p-value adjusted using the Bonferroni correction for multiple testing. Source data for (b-...
SH-SY5Y cells were passaged every 2–3 days and differentiated into a neuron-like state using a 5-day differentiation protocol with all-trans-retinoic acid (MedChemExpress, #HY-14649) as described previously33. For assessment of ATG9A translocation, differentiated SH-SY5Y cells were plated in ...
2. The clinical diagnosis status was used as the case status phenotype for this study, which was largely consistent with Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) score (Mirra et al., 1991), a semiquantitative measure of neuritic plaques where a neuropathologic ...
I took AP Calculus (BC), Chem, and Physics as a senior, and got 5, 5, 4. I placed out of the fresheman introductory courses, 1st year Math (Calc), Chemistry (but had to the Lab course), and one semester of Physics (I had to take the modern physics part which was intro QM)....
J. Biol. Chem. 254, 4739–4744 (1979). Article CAS PubMed Google Scholar Burley, S. K. et al. RCSB protein data bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, ...
In the heat map, blue indicates low expression and red indicates high expression. The black line in the topological graph indicates the interaction between genes, and the thicker the line is, the deeper the relationship is; the ellipse represents genes, and the color represents the score of ...
(n = 4 mice per group). Expression values are normalizedzscores.d, GSEA of the indicated signatures. FDR, color intensity of circles; NES, circle diameter. Blue and red indicate the group in which the signature was positively enriched; NES, normalized enrichment score; FDR, false ...
proteins, the false discovery rate was set to 1%, and a matching of at least two peptides, each with more than 28 ion score. The mass spectrometry analyses were repeated twice. Lentivirus infection The lentivirus constructs stably expressing shRNA-NKAP or shRNA-control was introduced into HCT...
protein has a solubility score of 0.555. Solubility-scaled proteins using the Protein-sol server that have a score greater than 0.45 indicate a higher solubility than the average solubleE. coliprotein from the experimental solubility dataset [45]; therefore, our designed protein has a high ...
HMM search was used to screen AP2/EREBP proteins that contain an AP2 domain with a cut-off score of 1e-5. The HMM file (PF02362, http://pfam.xfam.org/family/B3) was used to identify RAV proteins containing a B3 domain in addition to the AP2 domain from AP2/EREBP proteins. ...