Hello, Protégé cannot count items in a logical definitions, such that terms like GO:0062158 chloride:proton antiporter activity, which transports a positively charged and a negatively charged ions, ends up under both GO:0015491 cation:ca...
In order to achieve selective transport of multiple ion species in artificial ion channels, it is essential to understand the mechanism of ion transport in antiporters and symporters of natural membrane proteins. The CLC F F /H + Antiporter (CLC F ) has been attracting attention for its ...
Superposition of the individual domains of MdfA in the Ifand Ooconformations reveals significant deviations in the N-terminal domain (Supplementary Fig.2). The largest of these are found in TM5, which ends in the antiporter motif C 153AlaProXaaXaaGlyPro158 that is absent in symporters and unip...
A cotransporter (symporter) is a carrier protein that allows the transport of two different species (a solute and an ion) from one side of the membrane to the other at the same time[44,45]. Among many in existence, the most commonly studied cotransporters are the plasma membraneNa+–gluco...
Gao et al. now report a crystal structure of AdiC, an arginine:agmatine antiporter from E. coli. AdiC exhibits the same fold as that of the Na+-coupled symporters, including LeuT. It contains 12 transmembrane segments, forms a homodimer, and exists in an outward-facing, open conformation ...
The partial charges of the N and C termini of the short helices (IVc/IVp and XIc/XIp) are indicated. Recently, a bacterial homologue of the bile acid sodium symporter protein, ASBT, has been determined at 2.2 Å resolution. Overall, the architecture of this protein is very similar to ...
3) sodium/iodide symporter 钠/碘同向转运体 1. Effect of all-trans-retinoic acid on sodium/iodide symporter gene expression and radioiodide uptake of thyroid cancer cell line; 目的:探讨全反式维甲酸(ATRA)对甲状腺癌细胞株钠/碘同向转运体(NIS)基因表达、吸碘能力的影响,为ATRA用于放射性碘治疗...
Saline-alkali stress has adverse effects on plant growth. Some plant Na+/H+ antiporters were reported to be important in salt tolerance. However, it needs
Bacillus subtilis yheL encodes a Na(+)/H(+) antiporter, whereas its paralogue, yqkI, encodes a novel antiporter that achieves a simultaneous Na(+)/H(+) and malolactate antiport. B. subtilis yufR, a control in some experiments, encodes a Na(+)/malate symporter. YqkI complemented a mala...
The transporters of the MFS consist of uniporters, symporters, and antiporters, which share similarities in structures, predicted mechanism of transport, and highly conserved amino acid sequence motifs. In particular, the antiporter motif, called motif C, is found primarily in ...