GENESSURGICAL siteNUCLEOTIDE sequencingThe dramatic increase in infections caused by critically multidrug-resistant bacteria is a global health concern. In this study, we characterized the antimicrobial resistance genes (ARGs) of K. pneumoniae, P. mirabilis, E. cloacae and A. bauman...
and seafood. The main determinants of AMR are the antimicrobial resistance genes (ARGs), and food sources can broadly act as potential reservoirs of ARGs. To better understand the response of pathogens to antimicrobial agents, analysis of thetranscriptomicprofiles of ARGs in the food matrix has bee...
Antimicrobial resistance (AMR) is a global threat gaining more and more practical significance every year. Although antimicrobial resistance genes (ARGs) have been present ever since the appearance of the first living microorganisms1, the threat arising from AMR has stemmed from the daily use of ant...
Antimicrobial resistance (AMR) is a major threat to global health. Understanding the emergence, evolution, and transmission of individual antibiotic resistance genes (ARGs) is essential to develop sustainable strategies combatting this threat. Here, we use metagenomic sequencing to analyse ARGs in 757 s...
Methods that are used to characterise microbiomes and antimicrobial resistance genes (ARGs) in wastewater are not standardised. We used shotgun metagenomic sequencing (SM-Seq), RNA sequencing (RNA-seq) and targeted qPCR to compare microbial and ARG diversity in the influent to a municipal wastewate...
(transfer of genetic material from cell to cell) are two ways in which antimicrobial resistance genes (ARGs) can be acquired. They can both occur simultaneously. By acquiring new resistant genes and processes, HGT causes a population of microorganisms to have improved resistance profiles. HGT can...
Antimicrobial resistance has become a growing threat to public health [15,16]. A growing body of studies have shown that besides bacteria, phages also carry antimicrobial resistance genes (ARGs) in several environments, such as fresh water [17], marine habitats [18], raw sewage [19,20], and...
Additionally, levels of 10 antimicrobial resistance genes (ARGs) were assessed in all soil samples. Except for erm(B) and tet(M) at Nebraska, ARG increases after manure application dissipated before planting occurred. Treatment did not affect the following ARGs: aac(6′)‐Ie‐aph(2′′)‐Ia...
Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs pose serious threats to public health, highlighting the importance of identifying those that are high-risk. Here, we developed an ‘omics-based’ framework to evaluate ARG risk considering human-associated-enrichme...
The presence of extended-spectrum beta-lactamase (ESBL) and other antimicrobial resistance genes (ARGs) was also examined. METHODS AND RESULTS. A total of 606 fly- and 180 manure-derived strains were tested via disk diffusion for susceptibility to commonly administered antibiotics used in veterinary...