Fox JL (2013) Antimicrobial peptides stage a comeback. Nat Biotechnol 31(5):379–382. : 10.1038/nbt.2572Fox JL. 2013. Antimicrobial peptides stage a comeback . Nat. Biotechnol. 31 :379–382. 10.1038/nbt.2572 [ Cross Ref ]...
Antimicrobial peptides (AMPs) exhibit broad-spectrum antimicrobial activity, and have promise as new therapeutic agents. While the adult North American bullfrog (Rana [Lithobates] catesbeiana) is a prolific source of high-potency AMPs, the aquatic tadpol
The clinical translation of cationic α-helical antimicrobial peptides (AMPs) has been hindered by structural instability, proteolytic degradation and in vivo toxicity from nonspecific membrane lysis. Although analyses of hydrophobic content and charge d
While MDR, beta-lactams and peptide resistance genes were abundant and similar between biofilm and planktonic microbiomes, other abundantly detected ARG subtypes showed large differences between both microbial communities (Fig. 2C and Table S1F). Hence, planktonic microbiomes were clearly enriched in ...
Fox, J.L. Antimicrobial peptides stage a comeback. Nat. Biotechnol. 2013, 31, 379–382. [CrossRef] [PubMed] 36. Rozek, T.; Bowie, J.H.; Wallace, J.C.; Tyler, M.J. The antibiotic and anticancer active aurein peptides from the Australian Bell FrogsLitoria aurea andLitoria rani...
Orjih, “Heme Polymerase Activity and the Stage Specificity of Antimalarial Action of Chloroquine,” J. Pharm. Exp. Ther. 282(1): 108-112 (1997). Rohner et al., “Advantage of Combining Resin with Lytic BACTEC Blood Culture Media,” J. Clin. Micro. 35(10): 2634-2638 (1997). Roh...
The alarming worldwide increase in antibiotic resistance amongst microbial pathogens necessitates a search for new antimicrobial techniques, which will not be affected by, or indeed cause resistance themselves. Light-mediated photoinactivation is one such technique that takes advantage of the whole spectru...
the medical device may have antimicrobial peptides such as defensins, magainin and nisin; lytic bacteriophage; surfactants; adhesion blockers such as antibodies, oligosaccharides and glycolipids; oligonucleotides such as antisense RNA; efflux pump inhibitors; photosensitive dyes such as porphyrins; immune ...
Fox JL (2013) Antimicrobial peptides stage a comeback. Nat Biotechnol 31:379–382 CASPubMedGoogle Scholar Fregeau Gallagher NL, Sailer M, Niemczura WP, Nakashima TT, Stiles ME, Vederas JC (1997) Three-dimensional structure of leucocin A in trifluoroethanol and dodecylphosphocholine micelles: ...
Infection of bone is a severe complication due to the variety of bacteria causing it, their resistance against classical antibiotics, the formation of a biofilm and the difficulty to eradicate it. Antimicrobial peptides (AMPs) are naturally occurring pep