MAPPP is a bioinformatics tool for the prediction of potential antigenic epitopes presented on the cell surface by major histocompatibility complex class I (MHC I) molecules to CD8 positive T lymphocytes. It combines existing predictions for proteasomal cleavage with peptide anchoring to MHC I molecule...
To expedite discovery of such peptides, numerous bioinformatic tools have been developed to predict whether a given peptide is likely to form a stable binding interaction with MHC class II molecules. However, no prediction tool dedicated to the identification of bovine MHC (BoLA) class II-...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook Thesaurus Medical Encyclopedia Related to antigenic:antigenic determinant,Antigenic drift an·ti·gen (ăn′tĭ-jən)alsoan·ti·gene(-jēn′) n.
Define antigenic determinant. antigenic determinant synonyms, antigenic determinant pronunciation, antigenic determinant translation, English dictionary definition of antigenic determinant. n the specific part of an antigen molecule to which an antibody
Structural model and prediction of aggregation propensity of gp43 and its derived peptides Figure1a shows the primary sequence of gp43 (416 amino acids), highlighting in colored boxes the positions of the three peptides studied here, namely, P4 (green box), P10 (red box) and P23 (blue bo...
Peptides selected as SB according to NetMHCpan 4.1 prediction tool have been submitted to BLAST for a homology search against HIV-1 (taxid: 11,676) within the non-redundant protein sequences database (https://blast.ncbi.nlm.nih.gov/Blast.cgi). HIV-derived homologous sequences were analyzed...
Sign up with one click: Facebook Twitter Google Share on Facebook antigenic determinant Dictionary Thesaurus Medical Wikipedia Related to antigenic determinant:hapten,Clonal selection [‚an·tə¦jen·ik di′tər·mə·nənt] (immunology) ...
The second included the same fragment (TLIA) plus the peptide flanking regions of P10 based on the 9-mer core prediction (see Section 2.2.1), which were found useful for multiple-allele MHC II peptide engineering [31]. After selecting the two sets of positions, we performed two different ...
The Phyre 2 result is based in secondary structure prediction coupled to fold-recognition and three-dimensional structure predictions47. 1. Tjalsma, H., Bolhuis, A., Jongbloed, J. D., Bron, S. & van Dijl, J. M. Signal peptide- dependent protein transport in Bacillus subtilis: a genome...
Thus, the cross-reactivity of anti-SmSEA antibodies with Der f 15 seems likely to be due to recognition of glycan rather than peptide epitopes. Amid a wide-ranging smudge of cross-reactivity, three molecules of ~100 kDa, 30–35 kDa and 25–28 kDa in SEA reacted with antibodies ...