IMMUNOTHERAPYLIPOSOMESIMMUNOREGULATIONType 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing 尾-cells. To revert type 1 diabetes, the suppression of the autoimmune attack should be combined with a 尾-cell replacement strategy. It has been previously demonstrated that...
Abstract More than 25% of the population in industrialized countries suffers from immunoglobulin-E-mediated allergies. The antigen-specific immunotherapy that is in use at present involves the administration of allergen extracts to patients with the aim to cure allergic symptoms. However, the risk of...
CD40–B cells overcome current obstacles, such as the difficulty of isolation, generation, and long-term expansion observed with other APCs. Therefore, they are an excellent source of professional APCs for immune assessment, antigen discovery, and antigen-specific immunotherapy....
The primary objective of the trial (EudraCT No.: 2014-003520-44) is to evaluate safety and feasibility of active immunotherapy with antigen-loaded autologous DCs. The secondary objectives are to assess DC vaccination-induced T cell responses against WT1 and PRAME and to evaluate the clinical outco...
immune system),主要差别在於后者具有抗原独特性(antigen-specific)且具有记忆抗体细胞。先天 www.robotown.org.tw|基于 1 个网页 3. 原特异性 转殖的OT-I 小鼠为模式,测定e 蛋白对抗原特异性(antigen-specific) thuir.thu.edu.tw|基于 1 个网页
摘要: Antigen-specific cancer immunotherapy targeting minimal residual disease emerges as a novel treatment modality in multiple myeloma. Two candidate target antigens were identified: cancer/testis (CT) antigen NY-ESO-1 and BCMA, a plasma-cell membrane receptor....
Prostate-specific membrane antigen (PSMA) is expressed at high levels on malignant prostate cells and is likely an important therapeutic target for the treatment of prostate carcinoma. Current immunotherapy approaches to target PSMA include peptide, cell, vector or DNA-based vaccines as well as passiv...
Explore tumor antigen-derived peptides for cancer immunotherapy, vaccine development, and antigen targeting.
cancer immunotherapytumor-associated antigenanti-idiotypic antibodiesAnti-idiotypic antibodies (Ab2) that functionally mimic epitopes associated with human cancer cells are the most specific cancer vaccines currently available. Ab2 can induce specific humoral anti-tumor immunity in cancer patients. However,...
et al. LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control. j. immunotherapy cancer 3 (Suppl 2), P328 (2015). https://doi.org/10.1186/2051-1426-3-S2-P328 Download citation ...