The compositions exhibit immunological binding properties of antibody molecules capable of binding specifically to a human tumor cell displaying a MDR phenotype. A number of synthetic molecules are provided that include CDR and FR regions derived from same or different immunoglobulin moieties. Also ...
Nucleic acids encoding various proteases, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.Sriram BalasubramanianJohn FordDaniel M. GormanGerard ZurawskiUS...
Biosensors are devices that transduce a bio-recognition event, such as an antibody–antigen binding or the formation of a DNA duplex, into measurable electronic or opto-electronic signals. From: Trends in Biotechnology, 2005 About this pageSet alert Also in subject areas: Medicine and Dentistry Ne...
position, place - the particular portion of space occupied by something; "he put the lamp back in its place" active site - the part of an enzyme or antibody where the chemical reaction occurs close quarters - a situation of being uncomfortably close to someone or something locus - the speci...
(EGFR), stimulates proliferative signalling in cancer cells. 9E5 is an anti-EPR antibody that inhibits EGFR signalling by EPR but not by EGF56. The antigen-binding site of the antibody is formed by six loops referred to as complementary determining regions (CDR), with three (L1, L2, and ...
Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody ... Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and ...
Comprehend the functions of antibodies in the immune system. Learn about antibody binding and the processes of opsonization, agglutination and...
www.bioon.com.cn|基于7个网页 2. 抗原结合 AB是什么意思_ AB翻译_ AB解释... ... [=ammonium bemnzoate] 苯甲酸铵 [=antigen binding]抗原结合[=apex beat] 心尖搏动 ... zh-cn.oldict.com|基于 1 个网页 例句 释义: 全部,抗原粘合,抗原结合...
Here, we describe an antibody with an antigen binding site that binds two distinct proteins with high affinity. We isolated a variant of Herceptin, a therapeutic monoclonal antibody that binds the human epidermal growth factor receptor 2 (HER2), on the basis of its ability to simultaneously ...
20% of the antibody residues that actually bind the antigen fall outside the CDRs. However, virtually all antigen binding residues lie in regions of structural consensus across antibodies. Furthermore, we show that these regions of structural consensus which cover the antigen binding site are ...