The antigen-binding site of an N-propionylated polysialic acid-specific antibody protective against group B meningococci is consistent with extended epitopes. Johal AR,Jarrell HC,Letts JA,et al. Glycobiology . 2013Johal AR, Jarrell HC, Letts JA, Khieu NH, Landry RC, Jachymek W, Yang QL,...
antigenic determinant, epitope, determinant - the site on the surface of an antigen molecule to which an antibody attaches itself 3. site - a computer connected to the internet that maintains a series of web pages on the World Wide Web; "the Israeli web site was damaged by hostile hackers"...
GPRC5D is an atypical Class C orphan G protein-coupled receptor. Its high expression on the surface of multiple myeloma cells has rendered it an attractive target for therapeutic interventions, including monoclonal antibodies, CAR-T cells, and T-cell eng
antibody (ˈæntɪˌbɒdɪ) n,pl-bodies (Biochemistry) any of various proteins produced in the blood in response to the presence of an antigen. By becoming attached to antigens on infectious organisms antibodies can render them harmless or cause them to be destroyed. See alsoimmunog...
This binding malleability means that antibodies are an increasingly important category of biopharmaceuticals and biomarkers. We present Antibody i-Patch, a method that annotates the most likely antibody residues to be in contact with the antigen. We show that our predictions correlate with energetic ...
(ELISA). An assay that is used to detect the binding of antibody to antigens. Microneutralization assay An assay that measures the ability of serum or antibodies to neutralize influenza virus. Imprinting Describes a phenomenon in which the first exposure to influenza virus during childhood leaves ...
Here, we describe an antibody with an antigen binding site that binds two distinct proteins with high affinity. We isolated a variant of Herceptin, a therapeutic monoclonal antibody that binds the human epidermal growth factor receptor 2 (HER2), on the basis of its ability to simultaneously ...
Factor VII/VIIa: a new antigen in the anti-phospholipid antibody syndrome. Br J Haematol., 120 (2003), pp. 618-626 View in ScopusGoogle Scholar 22 J Arnout Antiphospholipid syndrome: diagnostic aspects of lupus anticoagulants. Thromb Haemost., 86 (2001), pp. 83-91 View in ScopusGoogle Sch...
An Enzyme Flow Immunoassay that Uses Beta-Galactosidase as the Label and a Cellobiose... Focuses on the development of a generic competitive enzyme flow immunoassay (EFIA) that can be used for antibody-antigen interaction. Preparation of tracer... Burestedt,Elisabeth,Nistor,... - 《Analytical ...
Anti-Chol-1 antigen, GQ1bα, antibodies are associated with Alzheimer’s disease. PLoS ONE 8, e63326 (2013). Article CAS PubMed PubMed Central Google Scholar Miura, Y. et al. Autoantibodies to GM1 and GQ1bα are not biological markers of Alzheimer’s disease. J. Alzheimers Dis. 42, ...