必应词典为您提供antifibrotic-agents的释义,网络释义: 抗纤维化药;抗纤维化药物;
Please accept my sincere greetings! I hope we decree by destiny! Here you have beautiful heart! 高! 佳丽: 你好! 原谅我结舌! 请接受我恳切的问候! 我希望我们由命运下旨! 您有美好的心脏![translate] aefforts to develop antifibrotic agents 努力开发antifibrotic代理[translate]...
Background The efficacy of antifibrotic agents in idiopathic pulmonary fibrosis (IPF) has been demonstrated and early introduction is recommended, especially in patients with preserved performance status (PS). We aimed to determine the proportion of untreated IPF cases using real-world data and to ass...
We tested the efficacy of 2 antifibrotic agents, the proline analogue cis-4- hydroxy- l- proline (cHyp) and the lathyrogen β-aminopropionitrile (BAPN), on experimental silicosis in hamsters. Silica (75 mg) was instilled intratracheally, and 3 months later lung hydroxyproline content, the...
In patients with idiopathic pulmonary fibrosis (IPF), the effects of antifibrotic agents on the prognosis remain unclear. This study aimed to investigate the impact of antifibrotic treatment on the risks of mortality, hospitalisation, and acute exacerbation in real-world patients with IPF. A total ...
Antioxidant agents separated from natural resources such as flavonoid, quercetin, silymarin or vitamin E have been reported to have positive effect on lipid peroxidation and hepatic fibrosis. And, N-acetylcysteine (NAC) has been confirmed to reduce oxidative stress and hepatic fibrosis in the early ...
In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridon... Lou,Qinghua,Meng,... 被引量: 13发表: 2012年 Long-term safety of pirfenidone in RECAP, an open-label extension study in patients...
Since dexamethasone was also able to block the TGF-β1-induced increase in collagen and noncollagen protein synthesis (Meisler et al., [1997] J. Invest. Dermatol. 108:285–289), these data indicate that phosphorothioate oligodeoxynucleotide antifibrotic agents mimic the inhibitory effect of ...
These antagonists alone or in combination with other agents can effectively prevent, mitigate or even reverse development of advanced fibrosis, such as fibrosis/cirrhosis of the liver and fibrosis of other organs, such as lungs, kidneys, intestine, pancreas, skin and arteries. 展开 ...
Another critical issue is that of the duration of antifibrotic therapy. Studies have shown that long-term administration of antifibrotic agents may be unwise, as beneficial short-term effects (e.g., increased drug delivery) may be overcome by detrimental long-term effects (e.g., accelerated tumo...