Recent data show that B cells and plasma cells located in tumours or in tumour-draining lymph nodes can have important roles in shaping antitumour immune responses. In tumour-associated tertiary lymphoid structures, T cells and B cells interact and under
The protective antibodies, secreted by preexisting long-lived plasma cells and reactivated antigen-experienced memory B cells, constitute the main humoral immune defense. Distinct from the primary antibody response, the humoral memory response is generated much faster and with greater magnitude, and it...
HOMING OF ANTIBODY-SECRETING CELLS (ASCs) The differentiation of a B cell into an antibody-secreting cell is accompanied by a large number of gene-expression plasma changes and involves the cell transforming from a small blast expressingIgas asurfacemolecule to a large cell that is full ofrough...
The protective antibodies, secreted by preexisting long-lived plasma cells and reactivated antigen-experienced memory B cells, constitute the main humoral immune defense. Distinct from the primary antibody response, the humoral memory response is generated much faster and with greater magnitude, and it...
Antibodies secreted into mucosal barriers serve to protect the host from a variety of pathogens, and are the basis for successful vaccines1. In type I mucosa (such as the intestinal tract), dimeric IgA secreted by local plasma cells is transported through polymeric immunoglobulin receptors2 and me...
Immunoglobulin E (IgE) antibodies have only been found in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). ...
These results clearly show that placental factors can up-regulate efficiently the synthesis of asymmetric IgG molecules of different isotypes secreted by plasma cells. 展开 DOI: 10.1016/0008-8749(92)90290-6 被引量: 51 年份: 1992 收藏 引用 批量引用 报错 分享 ...
1、immunoglobulin 1.Introduction 2.The structure of immunoglobulins 3.Heterogeneity of immunoglobulins 4.Functions of immunoglobulins 5.The structures and properties of immunoglobulin classes 6.Production of antibodies immunoglobulin Antibody(Ab) Globulin produced by plasma cells in response to antigen 2、 ...
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and ...
Antibody-secreting cells (ASC), plasmablasts and plasma cells, are terminally differentiated B cells responsible for large-scale production and secretion o... M Broketa,P Bruhns - 《Frontiers in Immunology》 被引量: 0发表: 2021年 A Microfluidic Chip for Screening and Sequencing of Monoclonal Ant...